Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | CK1 family protein kinase | 0.1392 | 1 | 0.5 |
Loa Loa (eye worm) | CK1/CK1/CK1-D protein kinase | 0.1392 | 1 | 0.5 |
Onchocerca volvulus | 0.1392 | 1 | 1 | |
Trichomonas vaginalis | CK1 family protein kinase | 0.1392 | 1 | 0.5 |
Echinococcus multilocularis | casein kinase I alpha | 0.1392 | 1 | 0.5 |
Giardia lamblia | Kinase, CK1 Casein kinase | 0.1392 | 1 | 0.5 |
Leishmania major | casein kinase, putative | 0.1392 | 1 | 0.5 |
Echinococcus granulosus | casein kinase I alpha | 0.1392 | 1 | 0.5 |
Entamoeba histolytica | casein kinase, putative | 0.1392 | 1 | 0.5 |
Trypanosoma cruzi | casein kinase, putative | 0.1392 | 1 | 1 |
Entamoeba histolytica | casein kinase 1, putative | 0.1392 | 1 | 0.5 |
Echinococcus multilocularis | casein kinase I alpha | 0.1392 | 1 | 0.5 |
Schistosoma mansoni | protein kinase | 0.1392 | 1 | 0.5 |
Echinococcus granulosus | casein kinase I alpha | 0.1392 | 1 | 0.5 |
Toxoplasma gondii | casein kinase I | 0.1392 | 1 | 0.5 |
Plasmodium vivax | casein kinase 1, putative | 0.1392 | 1 | 0.5 |
Echinococcus granulosus | casein kinase I delta | 0.1392 | 1 | 0.5 |
Loa Loa (eye worm) | CK1/CK1/CK1-A protein kinase | 0.1392 | 1 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1392 | 1 | 0.5 |
Echinococcus multilocularis | casein kinase I alpha | 0.1392 | 1 | 0.5 |
Trypanosoma cruzi | casein kinase, delta isoform, putative | 0.1392 | 1 | 1 |
Echinococcus multilocularis | casein kinase i | 0.1392 | 1 | 0.5 |
Echinococcus granulosus | casein kinase I alpha | 0.1392 | 1 | 0.5 |
Trypanosoma brucei | casein kinase I, isoform 2 | 0.1392 | 1 | 0.5 |
Trichomonas vaginalis | CK1 family protein kinase | 0.1392 | 1 | 0.5 |
Plasmodium falciparum | casein kinase 1 | 0.1392 | 1 | 0.5 |
Trypanosoma cruzi | casein kinase, putative | 0.1392 | 1 | 1 |
Trypanosoma cruzi | casein kinase, putative | 0.1392 | 1 | 1 |
Echinococcus multilocularis | casein kinase I delta | 0.1392 | 1 | 0.5 |
Echinococcus granulosus | casein kinase i | 0.1392 | 1 | 0.5 |
Echinococcus granulosus | casein kinase I delta | 0.1392 | 1 | 0.5 |
Brugia malayi | casein kinase I | 0.1392 | 1 | 0.5 |
Trypanosoma cruzi | casein kinase, putative | 0.1392 | 1 | 1 |
Loa Loa (eye worm) | CK1/CK1/CK1-A protein kinase | 0.1392 | 1 | 0.5 |
Echinococcus multilocularis | casein kinase I delta | 0.1392 | 1 | 0.5 |
Trypanosoma cruzi | casein kinase, putative | 0.1392 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 200 ug ml-1 | Antibacterial activity against Escherichia coli MTCC 443 assessed as growth inhibition by broth microdilution method | ChEMBL. | 23644214 |
MIC (functional) | = 1000 ug ml-1 | Antifungal activity against Candida albicans MTCC 227 assessed as growth inhibition by broth microdilution method | ChEMBL. | 23644214 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.