Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | solute carrier family 5 | 0.4117 | 0.5 | 0.5 |
Echinococcus multilocularis | sodium:myo inositol cotransporter | 0.4117 | 0.5 | 0.5 |
Echinococcus granulosus | sodium:myo inositol cotransporter | 0.4117 | 0.5 | 0.5 |
Echinococcus multilocularis | sodium:glucose cotransporter 2 | 0.4117 | 0.5 | 0.5 |
Schistosoma mansoni | inositol transporter | 0.4117 | 0.5 | 0.5 |
Echinococcus granulosus | sodium:glucose cotransporter 2 | 0.4117 | 0.5 | 0.5 |
Echinococcus multilocularis | solute carrier family 5 | 0.4117 | 0.5 | 0.5 |
Schistosoma mansoni | inositol transporter | 0.4117 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 4.7 % | 5-hydroxytryptamine 3 receptor antagonistic activity was measured by the inhibition of 5-HT-induced bradycardia after iv administration of 1000 ug/kg dose in urethane-anesthetized rats | ChEMBL. | 1732548 |
Inhibition (functional) | = 4.7 % | 5-hydroxytryptamine 3 receptor antagonistic activity was measured by the inhibition of 5-HT-induced bradycardia after iv administration of 1000 ug/kg dose in urethane-anesthetized rats | ChEMBL. | 1732548 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.