Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0451 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0367 | 0.7249 | 0.7249 |
Loa Loa (eye worm) | glutamate receptor | 0.0367 | 0.7241 | 0.7241 |
Schistosoma mansoni | d-amino acid oxidase | 0.0367 | 0.7249 | 0.7899 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.0451 | 1 | 1 |
Mycobacterium tuberculosis | Probable D-amino acid oxidase Aao | 0.0336 | 0.6253 | 0.5 |
Mycobacterium leprae | PROBABLE D-AMINO ACID OXIDASE AAO | 0.0367 | 0.7249 | 0.5 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0332 | 0.6119 | 0.8166 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0367 | 0.7241 | 1 |
Mycobacterium ulcerans | D-amino acid oxidase Aao | 0.0367 | 0.7249 | 0.5 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0417 | 0.8878 | 1 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0307 | 0.5304 | 0.5392 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.