Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | glycogen phosphorylase | 0.0258 | 1 | 1 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0258 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0213 | 0.3164 | 0.3164 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.0258 | 1 | 1 |
Schistosoma mansoni | glycogen phosphorylase | 0.0258 | 1 | 1 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.0258 | 1 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0258 | 1 | 1 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0258 | 1 | 0.5 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.0258 | 1 | 1 |
Echinococcus granulosus | glycogen phosphorylase | 0.0258 | 1 | 1 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0258 | 1 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0258 | 1 | 1 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.0258 | 1 | 1 |
Giardia lamblia | Glycogen phosphorylase | 0.0258 | 1 | 0.5 |
Echinococcus granulosus | glycogen phosphorylase | 0.0258 | 1 | 1 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0258 | 1 | 0.5 |
Chlamydia trachomatis | glycogen phosphorylase | 0.0258 | 1 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Intrinsic activity (functional) | = 29.88 % | Intrinsic activity at human dopamine D2L receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced adenylyl cyclase activity relative to quinpirole | ChEMBL. | 23618707 |
Intrinsic activity (functional) | = 68.7 % | Intrinsic activity at human dopamine D3 receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced adenylyl cyclase activity relative to quinpirole | ChEMBL. | 23618707 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.