Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | metabotropic glutamate receptor | 0.0506 | 0.2706 | 0.265 |
Echinococcus multilocularis | glycogen phosphorylase | 0.1742 | 1 | 1 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.1742 | 1 | 0.5 |
Chlamydia trachomatis | glycogen phosphorylase | 0.1742 | 1 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.1742 | 1 | 1 |
Schistosoma mansoni | glycogen phosphorylase | 0.1742 | 1 | 1 |
Schistosoma mansoni | glycogen phosphorylase | 0.0753 | 0.4163 | 0.4118 |
Giardia lamblia | Glycogen phosphorylase | 0.1742 | 1 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.1742 | 1 | 1 |
Echinococcus granulosus | glycogen phosphorylase | 0.1742 | 1 | 1 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.1742 | 1 | 1 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.1742 | 1 | 1 |
Loa Loa (eye worm) | glutamate receptor | 0.0061 | 0.0076 | 0.0076 |
Echinococcus granulosus | glycogen phosphorylase | 0.1742 | 1 | 1 |
Mycobacterium ulcerans | glycogen phosphorylase GlgP | 0.0753 | 0.4163 | 1 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.1742 | 1 | 1 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.0753 | 0.4163 | 1 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.1742 | 1 | 0.5 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.1742 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0162 | 0.0162 |
Brugia malayi | metabotropic glutamate receptor type 2 | 0.0075 | 0.0162 | 0.0162 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.1742 | 1 | 1 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.1742 | 1 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | Inhibition of human recombinant GST-tagged PTP1B using para-nitrophenyl phosphate as substrate assessed as release of para-nitrophenol at 10 uM after 10 mins by spectrophotometric analysis | ChEMBL. | 23691978 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.