Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | inward rectifying k channel family protein 1 | 0.0907 | 1 | 1 |
Echinococcus granulosus | potassium voltage gated channel subfamily A | 0.0461 | 0.0432 | 0.5 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0461 | 0.0432 | 0.5 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0461 | 0.0432 | 0.5 |
Brugia malayi | Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit | 0.0461 | 0.0432 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0907 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0907 | 1 | 1 |
Echinococcus multilocularis | potassium voltage gated channel protein | 0.0461 | 0.0432 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0907 | 1 | 0.5 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0461 | 0.0432 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.