Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | Janus kinase 2 | Starlite/ChEMBL | References |
Homo sapiens | Janus kinase 1 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | CMGC family protein kinase | 0.1077 | 0.4192 | 1 |
Plasmodium falciparum | casein kinase 2, alpha subunit | 0.1077 | 0.4192 | 1 |
Plasmodium vivax | casein kinase 2, alpha subunit, putative | 0.1077 | 0.4192 | 0.5 |
Echinococcus granulosus | proto oncogene serine:threonine protein kinase | 0.2535 | 1 | 1 |
Loa Loa (eye worm) | CMGC/CK2 protein kinase | 0.1077 | 0.4192 | 0.4069 |
Echinococcus multilocularis | voltage gated potassium channel | 0.0076 | 0.0208 | 0.0208 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0076 | 0.0208 | 0.0208 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1077 | 0.4192 | 1 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0076 | 0.0208 | 0.0208 |
Loa Loa (eye worm) | CAMK/CAMKL/PASK protein kinase | 0.0778 | 0.3003 | 0.2854 |
Schistosoma mansoni | hypothetical protein | 0.0076 | 0.0208 | 0.0208 |
Echinococcus granulosus | casein kinase ii subunit alpha | 0.1077 | 0.4192 | 0.4192 |
Echinococcus multilocularis | casein kinase ii subunit alpha | 0.1077 | 0.4192 | 0.4192 |
Brugia malayi | Casein kinase II, alpha chain | 0.1077 | 0.4192 | 0.4069 |
Entamoeba histolytica | casein kinase, putative | 0.1077 | 0.4192 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0076 | 0.0208 | 0.0208 |
Entamoeba histolytica | protein kinase, putative | 0.0026 | 0.0007 | 0.0017 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1077 | 0.4192 | 1 |
Echinococcus granulosus | voltage gated potassium channel | 0.0076 | 0.0208 | 0.0208 |
Entamoeba histolytica | SH2-protein kinase domain containing protein | 0.0026 | 0.0007 | 0.0017 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1077 | 0.4192 | 1 |
Trypanosoma cruzi | casein kinase II, putative | 0.1077 | 0.4192 | 1 |
Mycobacterium leprae | Possible transporter protein | 0.0076 | 0.0208 | 0.5 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.003 | 0.0024 | 0.0024 |
Loa Loa (eye worm) | CAMK/PIM protein kinase | 0.2535 | 1 | 1 |
Leishmania major | casein kinase II, putative | 0.1077 | 0.4192 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0076 | 0.0208 | 0.0208 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0076 | 0.0208 | 0.0208 |
Plasmodium vivax | unspecified product | 0.1077 | 0.4192 | 0.5 |
Trypanosoma brucei | Casein kinase II | 0.1077 | 0.4192 | 1 |
Loa Loa (eye worm) | CAMK/PIM protein kinase | 0.2535 | 1 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0076 | 0.0208 | 0.0208 |
Echinococcus granulosus | single minded 2 | 0.0076 | 0.0208 | 0.0208 |
Toxoplasma gondii | CMGC kinase, CK2 family | 0.1077 | 0.4192 | 1 |
Trypanosoma brucei | STE group serine/threonine-protein kinase, putative | 0.0096 | 0.0287 | 0.0685 |
Schistosoma mansoni | serine/threonine protein kinase | 0.2535 | 1 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0076 | 0.0208 | 0.0208 |
Brugia malayi | Serine/threonine-protein kinase Pim-3 | 0.2535 | 1 | 1 |
Echinococcus multilocularis | proto oncogene serine:threonine protein kinase | 0.2535 | 1 | 1 |
Entamoeba histolytica | protein kinase domain containing protein | 0.1077 | 0.4192 | 1 |
Onchocerca volvulus | Serine\/threonine protein kinase homolog | 0.2535 | 1 | 1 |
Schistosoma mansoni | 60S ribosomal protein L21 | 0.0076 | 0.0208 | 0.0208 |
Schistosoma mansoni | protein kinase | 0.1077 | 0.4192 | 0.4192 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1077 | 0.4192 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1077 | 0.4192 | 1 |
Giardia lamblia | Kinase, CMGC CK2 | 0.1077 | 0.4192 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.1077 | 0.4192 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.