Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | [G-protein-coupledreceptor] kinase | 0.2046 | 0.8892 | 1 |
Echinococcus multilocularis | beta adrenergic receptor kinase | 0.0232 | 0.0027 | 0.003 |
Loa Loa (eye worm) | AGC/GRK/BARK protein kinase | 0.0232 | 0.0027 | 0.0027 |
Entamoeba histolytica | hypothetical protein | 0.0227 | 0 | 0.5 |
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.2046 | 0.8892 | 0.8892 |
Echinococcus multilocularis | G protein coupled receptor kinase 6 | 0.2046 | 0.8892 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0232 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.2046 | 0.8892 | 0.8892 |
Entamoeba histolytica | hypothetical protein | 0.0227 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0227 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0227 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0227 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0227 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0227 | 0 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0232 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.2272 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0227 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0227 | 0 | 0.5 |
Loa Loa (eye worm) | G protein-coupled receptor kinase 1 | 0.2046 | 0.8892 | 0.8892 |
Echinococcus granulosus | beta-adrenergic receptor kinase | 0.0232 | 0.0027 | 0.003 |
Schistosoma mansoni | serine/threonine protein kinase | 0.2272 | 1 | 1 |
Trichomonas vaginalis | regulator of G protein signaling 5, rgs5, putative | 0.0227 | 0 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 1 mg/ml | Antimicrobial activity against Escherichia coli assessed as growth inhibition by agar dilution method | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.