Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | glycogen phosphorylase, putative | 0.1301 | 0.5 | 0.5 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.1301 | 0.5 | 0.5 |
Echinococcus granulosus | glycogen phosphorylase | 0.1301 | 0.5 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.1301 | 0.5 | 0.5 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.1301 | 0.5 | 0.5 |
Chlamydia trachomatis | glycogen phosphorylase | 0.1301 | 0.5 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.1301 | 0.5 | 0.5 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.1301 | 0.5 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.1301 | 0.5 | 0.5 |
Echinococcus granulosus | glycogen phosphorylase | 0.1301 | 0.5 | 0.5 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.1301 | 0.5 | 0.5 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.1301 | 0.5 | 0.5 |
Giardia lamblia | Glycogen phosphorylase | 0.1301 | 0.5 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.1301 | 0.5 | 0.5 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.1301 | 0.5 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.1301 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | > 125 uM | Inhibition of human recombinant LSD1 (157 to 852 aa) expressed in Escherichia coli BL21(DE) using H3K4me2 as substrate by fluorescence assay | ChEMBL. | 24131029 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.