Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | esterase, putative | 0.0365 | 0.8496 | 1 |
Plasmodium falciparum | lysophospholipase, putative | 0.0365 | 0.8496 | 1 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.042 | 1 | 1 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.042 | 1 | 1 |
Chlamydia trachomatis | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.0051 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0365 | 0.8496 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0365 | 0.8496 | 0.5 |
Entamoeba histolytica | hydrolase, alpha/beta fold family domain containing protein | 0.0365 | 0.8496 | 0.5 |
Trypanosoma cruzi | monoglyceride lipase, putative | 0.0365 | 0.8496 | 1 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.042 | 1 | 1 |
Plasmodium vivax | PST-A protein | 0.0365 | 0.8496 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0365 | 0.8496 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.042 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0051 | 0 | 0.5 |
Mycobacterium tuberculosis | Possible lysophospholipase | 0.0365 | 0.8496 | 1 |
Schistosoma mansoni | amidase | 0.042 | 1 | 1 |
Trypanosoma brucei | monoglyceride lipase, putative | 0.0365 | 0.8496 | 1 |
Mycobacterium leprae | POSSIBLE LYSOPHOSPHOLIPASE | 0.0365 | 0.8496 | 1 |
Entamoeba histolytica | hydrolase, alpha/beta fold family domain containing protein | 0.0365 | 0.8496 | 0.5 |
Trichomonas vaginalis | valacyclovir hydrolase, putative | 0.0365 | 0.8496 | 0.5 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.042 | 1 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0365 | 0.8496 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0365 | 0.8496 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0365 | 0.8496 | 0.5 |
Plasmodium falciparum | lysophospholipase, putative | 0.0365 | 0.8496 | 1 |
Treponema pallidum | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0051 | 0 | 0.5 |
Trypanosoma brucei | monoglyceride lipase, putative | 0.0365 | 0.8496 | 1 |
Mycobacterium ulcerans | lysophospholipase | 0.0365 | 0.8496 | 1 |
Plasmodium falciparum | lysophospholipase, putative | 0.0365 | 0.8496 | 1 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.042 | 1 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0365 | 0.8496 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0365 | 0.8496 | 0.5 |
Leishmania major | monoglyceride lipase, putative | 0.0365 | 0.8496 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.