Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | solute carrier family 5 | 0.4233 | 0.5 | 0.5 |
Echinococcus granulosus | solute carrier family 5 | 0.4233 | 0.5 | 0.5 |
Echinococcus granulosus | sodium:myo inositol cotransporter | 0.4233 | 0.5 | 0.5 |
Schistosoma mansoni | inositol transporter | 0.4233 | 0.5 | 0.5 |
Echinococcus multilocularis | sodium:myo inositol cotransporter | 0.4233 | 0.5 | 0.5 |
Echinococcus multilocularis | sodium:glucose cotransporter 2 | 0.4233 | 0.5 | 0.5 |
Schistosoma mansoni | inositol transporter | 0.4233 | 0.5 | 0.5 |
Echinococcus granulosus | sodium:glucose cotransporter 2 | 0.4233 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | Antimicrobial activity against Escherichia coli ATCC 25922 assessed as growth inhibition after 24 hr by NCCLS broth dilution method | ChEMBL. | No reference | |
MIC (functional) | = 25 ug ml-1 | Antimicrobial activity against Escherichia coli ATCC 25922 assessed as growth inhibition after 24 hr by NCCLS broth dilution method | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.