Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Trypsin family protein | 0.0225 | 0.2073 | 0.2073 |
Plasmodium falciparum | cysteine repeat modular protein 1 | 0.0055 | 0.0109 | 0.5 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.091 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0225 | 0.2073 | 0.2073 |
Brugia malayi | Kringle domain containing protein | 0.0055 | 0.0109 | 0.0109 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.091 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0109 | 0.0109 |
Onchocerca volvulus | 0.0225 | 0.2073 | 1 | |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.091 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0055 | 0.0109 | 0.0109 |
Trypanosoma brucei | protein tyrosine phosphatase 1 | 0.0046 | 0 | 0.5 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.0055 | 0.0109 | 0.0109 |
Schistosoma mansoni | protein tyrosine phosphatase n11 (shp2) | 0.091 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0225 | 0.2073 | 0.2073 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0055 | 0.0109 | 0.0109 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0055 | 0.0109 | 1 |
Trichomonas vaginalis | pten, drome, putative | 0.0046 | 0 | 0.5 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.091 | 1 | 1 |
Onchocerca volvulus | 0.019 | 0.1668 | 0.8046 | |
Leishmania major | hypothetical protein, conserved | 0.0055 | 0.0109 | 1 |
Giardia lamblia | Protein tyrosine phosphatase | 0.0046 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0225 | 0.2073 | 0.2073 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0046 | 0 | 0.5 |
Entamoeba histolytica | Pten 3-phosphoinositide phosphatase, putative | 0.0046 | 0 | 0.5 |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.0055 | 0.0109 | 0.5 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0046 | 0 | 0.5 |
Brugia malayi | Protein kinase domain containing protein | 0.0055 | 0.0109 | 0.0109 |
Echinococcus granulosus | tissue type plasminogen activator | 0.0055 | 0.0109 | 0.0109 |
Onchocerca volvulus | 0.0055 | 0.0109 | 0.0524 | |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0225 | 0.2073 | 0.2073 |
Toxoplasma gondii | PAN domain-containing protein | 0.0635 | 0.6823 | 1 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.091 | 1 | 1 |
Toxoplasma gondii | PAN domain-containing protein | 0.0635 | 0.6823 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.