Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.176 | 0.2646 | 0.5 |
Trypanosoma brucei | metacaspase | 0.176 | 0.2646 | 0.5 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.015 | 0.0086 | 0.0086 |
Trichomonas vaginalis | conserved hypothetical protein | 0.176 | 0.2646 | 0.5 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.176 | 0.2646 | 0.5 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.176 | 0.2646 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.176 | 0.2646 | 0.5 |
Trypanosoma cruzi | metacaspase, putative | 0.176 | 0.2646 | 0.5 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.176 | 0.2646 | 0.5 |
Echinococcus multilocularis | caspase 3, apoptosis cysteine peptidase | 0.6387 | 1 | 1 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.176 | 0.2646 | 0.5 |
Trypanosoma brucei | Metacaspase-4 | 0.176 | 0.2646 | 0.5 |
Brugia malayi | mucosa associated lymphoid tissue lymphoma translocation protein 1 | 0.176 | 0.2646 | 0.9458 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.1856 | 0.2798 | 0.2798 |
Trichomonas vaginalis | conserved hypothetical protein | 0.176 | 0.2646 | 0.5 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.176 | 0.2646 | 0.5 |
Leishmania major | metacaspase, putative | 0.176 | 0.2646 | 0.5 |
Schistosoma mansoni | caspase-3 (C14 family) | 0.6387 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1856 | 0.2798 | 1 |
Echinococcus multilocularis | caspase | 0.6387 | 1 | 1 |
Echinococcus granulosus | caspase 2 | 0.1856 | 0.2798 | 0.2798 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.176 | 0.2646 | 0.5 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.176 | 0.2646 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.176 | 0.2646 | 0.9458 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.176 | 0.2646 | 0.5 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.6387 | 1 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.176 | 0.2646 | 0.5 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.176 | 0.2646 | 0.5 |
Schistosoma mansoni | subfamily C14A unassigned peptidase (C14 family) | 0.176 | 0.2646 | 0.2646 |
Onchocerca volvulus | Cell death protein 3 homolog | 0.1856 | 0.2798 | 1 |
Trypanosoma cruzi | metacaspase, putative | 0.176 | 0.2646 | 0.5 |
Trypanosoma cruzi | metacaspase, putative | 0.176 | 0.2646 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.176 | 0.2646 | 0.5 |
Trypanosoma brucei | metacaspase MCA2 | 0.176 | 0.2646 | 0.5 |
Trypanosoma cruzi | metacaspase 5, putative | 0.176 | 0.2646 | 0.5 |
Trypanosoma brucei | metacaspase MCA3 | 0.176 | 0.2646 | 0.5 |
Echinococcus granulosus | caspase 3 | 0.4627 | 0.7202 | 0.7202 |
Trypanosoma cruzi | metacaspase 5, putative | 0.176 | 0.2646 | 0.5 |
Brugia malayi | Cell death protein 3 precursor | 0.1856 | 0.2798 | 1 |
Trypanosoma brucei | metacaspase 5, putative | 0.176 | 0.2646 | 0.5 |
Plasmodium vivax | metacaspase 1, putative | 0.176 | 0.2646 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.176 | 0.2646 | 0.5 |
Trypanosoma cruzi | metacaspase, putative | 0.176 | 0.2646 | 0.5 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.176 | 0.2646 | 0.5 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.176 | 0.2646 | 0.5 |
Echinococcus multilocularis | caspase 8 | 0.176 | 0.2646 | 0.2646 |
Echinococcus multilocularis | caspase 3 | 0.4627 | 0.7202 | 0.7202 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.015 | 0.0086 | 0.0086 |
Echinococcus granulosus | caspase | 0.6387 | 1 | 1 |
Echinococcus multilocularis | caspase 2 | 0.1856 | 0.2798 | 0.2798 |
Plasmodium falciparum | metacaspase-like protein | 0.176 | 0.2646 | 0.5 |
Plasmodium falciparum | metacaspase 1 | 0.176 | 0.2646 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.176 | 0.2646 | 0.5 |
Echinococcus granulosus | caspase 8 | 0.176 | 0.2646 | 0.2646 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.