Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | serine/threonine protein kinase | 0.1724 | 1 | 1 |
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.0444 | 0.1362 | 1 |
Echinococcus multilocularis | G protein coupled receptor kinase 1 | 0.1522 | 0.8638 | 0.8638 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1724 | 1 | 1 |
Echinococcus multilocularis | beta adrenergic receptor kinase | 0.1724 | 1 | 1 |
Loa Loa (eye worm) | AGC/GRK/BARK protein kinase | 0.1724 | 1 | 1 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.0444 | 0.1362 | 0.1362 |
Echinococcus granulosus | G protein coupled receptor kinase 1 | 0.1522 | 0.8638 | 0.8638 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (ADMET) | = 20 % | Toxicity in Oryza sativa (rice) plant assessed as inhibition at 150 g/hectare | ChEMBL. | 22816730 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.