Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | NADPH oxidoreductase, putative | 0.0159 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0159 | 0 | 0.5 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.1223 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0464 | 0.2867 | 0.2608 |
Loa Loa (eye worm) | hypothetical protein | 0.0464 | 0.2867 | 0.2608 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0159 | 0 | 0.5 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.1223 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0464 | 0.2867 | 0.2608 |
Brugia malayi | Kringle domain containing protein | 0.1223 | 1 | 1 |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.1223 | 1 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0159 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0159 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0159 | 0 | 0.5 |
Trichomonas vaginalis | NAD(P)H dehydrogenase, putative | 0.0159 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0159 | 0 | 0.5 |
Onchocerca volvulus | 0.0464 | 0.2867 | 0.2608 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0159 | 0 | 0.5 |
Brugia malayi | Trypsin family protein | 0.0464 | 0.2867 | 0.2608 |
Giardia lamblia | NADPH oxidoreductase, putative | 0.0159 | 0 | 0.5 |
Onchocerca volvulus | 0.0268 | 0.1027 | 0.0701 | |
Trypanosoma cruzi | hypothetical protein, conserved | 0.1223 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0464 | 0.2867 | 0.2608 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0159 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0159 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.1223 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0159 | 0 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0196 | 0.035 | 0.5 |
Toxoplasma gondii | kringle domain-containing protein | 0.1223 | 1 | 0.5 |
Giardia lamblia | NADPH oxidoreductase, putative | 0.0159 | 0 | 0.5 |
Plasmodium falciparum | cysteine repeat modular protein 1 | 0.1223 | 1 | 0.5 |
Onchocerca volvulus | 0.1223 | 1 | 1 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0159 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0159 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1223 | 1 | 1 |
Trichomonas vaginalis | NAD(P)H dehydrogenase, putative | 0.0159 | 0 | 0.5 |
Echinococcus granulosus | tissue type plasminogen activator | 0.1223 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0159 | 0 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.1223 | 1 | 0.5 |
Trichomonas vaginalis | NAD(P)H dehydrogenase, putative | 0.0159 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.