Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | glycogen phosphorylase | 0.011 | 0.5 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.011 | 0.5 | 0.5 |
Chlamydia trachomatis | glycogen phosphorylase | 0.011 | 0.5 | 0.5 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.011 | 0.5 | 0.5 |
Echinococcus granulosus | glycogen phosphorylase | 0.011 | 0.5 | 0.5 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.011 | 0.5 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.011 | 0.5 | 0.5 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.011 | 0.5 | 0.5 |
Giardia lamblia | Glycogen phosphorylase | 0.011 | 0.5 | 0.5 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.011 | 0.5 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.011 | 0.5 | 0.5 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.011 | 0.5 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.011 | 0.5 | 0.5 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.011 | 0.5 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.011 | 0.5 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.011 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MTD (ADMET) | = 5 g/acre | Phytotoxicity against two-leaf stage Oryza sativa cv. Nihonbare (rice) planted 1 cm depth measured after 20 to 25 weeks | ChEMBL. | No reference |
MTD (ADMET) | = 10 g/acre | Phytotoxicity against two-leaf stage Oryza sativa cv. Nihonbare (rice) planted 3 cm depth measured after 20 to 25 weeks | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.