Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.1691 | 0.1691 |
Trichomonas vaginalis | AGC family protein kinase | 0.0332 | 1 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0124 | 0.296 | 0.1007 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0064 | 0.0933 | 0.0933 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.1691 | 0.1691 |
Trichomonas vaginalis | AGC family protein kinase | 0.0332 | 1 | 1 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0068 | 0.1064 | 0.1064 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0332 | 1 | 1 |
Loa Loa (eye worm) | AUR protein kinase | 0.0332 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0101 | 0.2172 | 0.2172 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.0101 | 0.2172 | 0.2172 |
Entamoeba histolytica | serine/threonine- protein kinase 6, putative | 0.0332 | 1 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0332 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0101 | 0.2172 | 0.2172 |
Onchocerca volvulus | 0.0124 | 0.296 | 1 | |
Loa Loa (eye worm) | cuticular endochitinase | 0.0078 | 0.1406 | 0.1406 |
Entamoeba histolytica | chitinase, putative | 0.0078 | 0.1406 | 0.1406 |
Echinococcus granulosus | serine:threonine protein kinase 12 B | 0.0332 | 1 | 1 |
Onchocerca volvulus | Putative endochitinase | 0.0088 | 0.1725 | 0.2052 |
Brugia malayi | endochitinase | 0.0078 | 0.1406 | 0.1406 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0101 | 0.2172 | 0.2172 |
Trichomonas vaginalis | AGC family protein kinase | 0.0101 | 0.2172 | 0.2172 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0332 | 1 | 1 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.0068 | 0.1064 | 0.1064 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.009 | 0.1822 | 0.0848 |
Trypanosoma cruzi | aurora B kinase, putative | 0.0332 | 1 | 1 |
Echinococcus granulosus | serine threonine protein kinase nrc | 0.0068 | 0.1064 | 0.1064 |
Trichomonas vaginalis | AGC family protein kinase | 0.0332 | 1 | 1 |
Echinococcus granulosus | serine/threonine protein kinase | 0.0068 | 0.1064 | 0.1064 |
Entamoeba histolytica | protein kinase, putative | 0.0101 | 0.2172 | 0.2172 |
Onchocerca volvulus | 0.0124 | 0.296 | 1 | |
Mycobacterium ulcerans | chitinase/cellulase | 0.0067 | 0.1017 | 0.5 |
Loa Loa (eye worm) | AUR protein kinase | 0.0332 | 1 | 1 |
Entamoeba histolytica | serine/threonine protein kinase 6, putative | 0.0332 | 1 | 1 |
Leishmania major | protein kinase, putative | 0.0332 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0101 | 0.2172 | 0.2172 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.009 | 0.1822 | 0.0484 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.0332 | 1 | 1 |
Echinococcus multilocularis | Glutaredoxin protein 5 | 0.0064 | 0.0933 | 0.0933 |
Trypanosoma brucei | aurora B kinase | 0.0332 | 1 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.009 | 0.1822 | 0.1822 |
Entamoeba histolytica | protein kinase, putative | 0.0101 | 0.2172 | 0.2172 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.009 | 0.1822 | 0.1822 |
Entamoeba histolytica | protein kinase domain containing protein | 0.009 | 0.1822 | 0.1822 |
Echinococcus multilocularis | rac serine:threonine kinase | 0.0068 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | AUR protein kinase | 0.0332 | 1 | 1 |
Echinococcus granulosus | Hepatocellular carcinoma associated antigen 59 | 0.0124 | 0.296 | 0.296 |
Entamoeba histolytica | protein kinase 2, putative | 0.0068 | 0.1064 | 0.1064 |
Plasmodium falciparum | serine/threonine protein kinase, putative | 0.0332 | 1 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0101 | 0.2172 | 0.2172 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.0068 | 0.1064 | 0.1064 |
Schistosoma mansoni | protein kinase | 0.0332 | 1 | 1 |
Entamoeba histolytica | protein kinase , putative | 0.0332 | 1 | 1 |
Mycobacterium ulcerans | chitinase/cellulase | 0.0067 | 0.1017 | 0.5 |
Echinococcus granulosus | nervana 2 | 0.0064 | 0.0933 | 0.0933 |
Loa Loa (eye worm) | microfilarial chitinase | 0.0076 | 0.1336 | 0.1336 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.296 | 0.296 |
Schistosoma mansoni | hypothetical protein | 0.0124 | 0.296 | 0.296 |
Plasmodium vivax | serine/threonine protein kinase 6, putative | 0.0332 | 1 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase 12 B | 0.0332 | 1 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.009 | 0.1822 | 0.1822 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0064 | 0.0933 | 0.0933 |
Entamoeba histolytica | protein kinase, putative | 0.0332 | 1 | 1 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.009 | 0.1822 | 0.0848 |
Schistosoma mansoni | serine/threonine protein kinase | 0.009 | 0.1822 | 0.1822 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0101 | 0.2172 | 0.2172 |
Plasmodium falciparum | conserved protein, unknown function | 0.0124 | 0.296 | 0.2122 |
Onchocerca volvulus | Putative endochitinase | 0.0088 | 0.1725 | 0.2052 |
Entamoeba histolytica | serine/threonine- protein kinase 6 , putative | 0.0332 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0332 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0101 | 0.2172 | 0.2172 |
Onchocerca volvulus | Putative endochitinase | 0.0088 | 0.1725 | 0.2052 |
Brugia malayi | endochitinase | 0.0088 | 0.1725 | 0.1725 |
Echinococcus granulosus | dual specificity | 0.009 | 0.1822 | 0.1822 |
Echinococcus granulosus | nervana 2 | 0.0064 | 0.0933 | 0.0933 |
Entamoeba histolytica | protein kinase, putative | 0.009 | 0.1822 | 0.1822 |
Echinococcus multilocularis | dual specificity | 0.009 | 0.1822 | 0.1822 |
Entamoeba histolytica | protein kinase, putative | 0.0101 | 0.2172 | 0.2172 |
Echinococcus multilocularis | Hepatocellular carcinoma associated antigen 59 | 0.0124 | 0.296 | 0.296 |
Loa Loa (eye worm) | chitinase I | 0.0078 | 0.1406 | 0.1406 |
Echinococcus granulosus | aurora kinase A | 0.0332 | 1 | 1 |
Toxoplasma gondii | aurora kinase | 0.0332 | 1 | 1 |
Mycobacterium tuberculosis | Possible chitinase | 0.0067 | 0.1017 | 0.5 |
Giardia lamblia | Aurora kinase | 0.0332 | 1 | 1 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0101 | 0.2172 | 0.0427 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0068 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.1017 | 0.1017 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0068 | 0.1064 | 0.1064 |
Trichomonas vaginalis | AGC family protein kinase | 0.0101 | 0.2172 | 0.2172 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.296 | 0.296 |
Trichomonas vaginalis | AGC family protein kinase | 0.0101 | 0.2172 | 0.2172 |
Echinococcus granulosus | Glutaredoxin protein 5 | 0.0064 | 0.0933 | 0.0933 |
Brugia malayi | serine/threonine kinase 12 | 0.0332 | 1 | 1 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0068 | 0.1064 | 0.1064 |
Echinococcus multilocularis | aurora kinase A | 0.0332 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.009 | 0.1822 | 0.1822 |
Brugia malayi | Hepatocellular carcinoma-associated antigen 59 family protein | 0.0124 | 0.296 | 0.296 |
Plasmodium vivax | hypothetical protein, conserved | 0.0124 | 0.296 | 0.2122 |
Brugia malayi | Endochitinase | 0.0088 | 0.1725 | 0.1725 |
Echinococcus multilocularis | nervana 2 | 0.0064 | 0.0933 | 0.0933 |
Echinococcus multilocularis | nervana 2 | 0.0064 | 0.0933 | 0.0933 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.