Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | AGC family protein kinase | 0.0187 | 1 | 1 |
Schistosoma mansoni | protein kinase | 0.0187 | 1 | 1 |
Loa Loa (eye worm) | AUR protein kinase | 0.0187 | 1 | 1 |
Echinococcus granulosus | serine:threonine protein kinase 12 B | 0.0187 | 1 | 1 |
Onchocerca volvulus | 0.0131 | 0.5745 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.1468 | 0.1468 |
Entamoeba histolytica | protein kinase, putative | 0.0187 | 1 | 1 |
Onchocerca volvulus | 0.0131 | 0.5745 | 1 | |
Entamoeba histolytica | protein kinase , putative | 0.0187 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.1468 | 0.1468 |
Entamoeba histolytica | serine/threonine- protein kinase 6, putative | 0.0187 | 1 | 1 |
Brugia malayi | serine/threonine kinase 12 | 0.0187 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0139 | 0.6305 | 0.6305 |
Entamoeba histolytica | serine/threonine- protein kinase 6 , putative | 0.0187 | 1 | 1 |
Onchocerca volvulus | 0.0131 | 0.5745 | 1 | |
Echinococcus multilocularis | rac serine:threonine kinase | 0.0093 | 0.2796 | 0.0261 |
Brugia malayi | hypothetical protein | 0.0075 | 0.1468 | 0.1468 |
Trichomonas vaginalis | AGC family protein kinase | 0.0139 | 0.6305 | 0.6305 |
Onchocerca volvulus | 0.0075 | 0.1468 | 0.2556 | |
Trichomonas vaginalis | AGC family protein kinase | 0.0139 | 0.6305 | 0.6305 |
Brugia malayi | LBP / BPI / CETP family, N-terminal domain containing protein | 0.0131 | 0.5745 | 0.5745 |
Trichomonas vaginalis | AGC family protein kinase | 0.0139 | 0.6305 | 0.6305 |
Entamoeba histolytica | protein kinase, putative | 0.0187 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0187 | 1 | 1 |
Plasmodium vivax | serine/threonine protein kinase 6, putative | 0.0187 | 1 | 1 |
Giardia lamblia | Aurora kinase | 0.0187 | 1 | 1 |
Onchocerca volvulus | 0.0131 | 0.5745 | 1 | |
Echinococcus granulosus | aurora kinase A | 0.0187 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.1468 | 0.1468 |
Entamoeba histolytica | protein kinase, putative | 0.0139 | 0.6305 | 0.4871 |
Onchocerca volvulus | 0.0131 | 0.5745 | 1 | |
Brugia malayi | LBP / BPI / CETP family, C-terminal domain containing protein | 0.0075 | 0.1468 | 0.1468 |
Brugia malayi | LBP / BPI / CETP family, N-terminal domain containing protein | 0.0131 | 0.5745 | 0.5745 |
Trichomonas vaginalis | AGC family protein kinase | 0.0139 | 0.6305 | 0.6305 |
Loa Loa (eye worm) | LBP/BPI/CETP family domain-containing protein | 0.0131 | 0.5745 | 0.5745 |
Trichomonas vaginalis | AGC family protein kinase | 0.0187 | 1 | 1 |
Onchocerca volvulus | 0.0131 | 0.5745 | 1 | |
Entamoeba histolytica | serine/threonine protein kinase 6, putative | 0.0187 | 1 | 1 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.0187 | 1 | 1 |
Brugia malayi | LBP / BPI / CETP family, C-terminal domain containing protein | 0.0075 | 0.1468 | 0.1468 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.0093 | 0.2796 | 0.0261 |
Brugia malayi | Protein kinase domain containing protein | 0.0139 | 0.6305 | 0.6305 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.0093 | 0.2796 | 0.0261 |
Loa Loa (eye worm) | AUR protein kinase | 0.0187 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.1468 | 0.1468 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0187 | 1 | 1 |
Brugia malayi | LBP / BPI / CETP family, C-terminal domain containing protein | 0.0075 | 0.1468 | 0.1468 |
Brugia malayi | LBP / BPI / CETP family, C-terminal domain containing protein | 0.0131 | 0.5745 | 0.5745 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.0139 | 0.6305 | 0.6305 |
Trypanosoma brucei | aurora B kinase | 0.0187 | 1 | 1 |
Leishmania major | protein kinase, putative | 0.0187 | 1 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0187 | 1 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0139 | 0.6305 | 0.4871 |
Echinococcus granulosus | serine/threonine protein kinase | 0.0093 | 0.2796 | 0.0261 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0139 | 0.6305 | 0.6305 |
Echinococcus multilocularis | aurora kinase A | 0.0187 | 1 | 1 |
Plasmodium falciparum | serine/threonine protein kinase, putative | 0.0187 | 1 | 1 |
Onchocerca volvulus | 0.0131 | 0.5745 | 1 | |
Trypanosoma cruzi | aurora B kinase, putative | 0.0187 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0075 | 0.1468 | 0.1468 |
Trichomonas vaginalis | AGC family protein kinase | 0.0187 | 1 | 1 |
Onchocerca volvulus | 0.0131 | 0.5745 | 1 | |
Onchocerca volvulus | 0.0075 | 0.1468 | 0.2556 | |
Loa Loa (eye worm) | LBP/BPI/CETP family domain-containing protein | 0.0075 | 0.1468 | 0.1468 |
Loa Loa (eye worm) | hypothetical protein | 0.0131 | 0.5745 | 0.5745 |
Entamoeba histolytica | protein kinase, putative | 0.0139 | 0.6305 | 0.4871 |
Loa Loa (eye worm) | LBP/BPI/CETP family domain-containing protein | 0.0075 | 0.1468 | 0.1468 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0139 | 0.6305 | 0.6305 |
Echinococcus granulosus | serine threonine protein kinase nrc | 0.0093 | 0.2796 | 0.0261 |
Trichomonas vaginalis | AGC family protein kinase | 0.0139 | 0.6305 | 0.6305 |
Echinococcus multilocularis | serine:threonine protein kinase 12 B | 0.0187 | 1 | 1 |
Toxoplasma gondii | aurora kinase | 0.0187 | 1 | 1 |
Loa Loa (eye worm) | AUR protein kinase | 0.0187 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.1468 | 0.1468 |
Trichomonas vaginalis | AGC family protein kinase | 0.0139 | 0.6305 | 0.6305 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.