Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tyrosine kinase | 0.0169 | 0.1684 | 0.162 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0394 | 0.7053 | 0.7031 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0394 | 0.7053 | 0.7053 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.0517 | 1 | 1 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0171 | 0.1727 | 0.1663 |
Loa Loa (eye worm) | hypothetical protein | 0.0167 | 0.1645 | 0.1581 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.0517 | 1 | 1 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0517 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0517 | 1 | 0.5 |
Brugia malayi | Histone deacetylase family protein | 0.0394 | 0.7053 | 0.7031 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0517 | 1 | 0.5 |
Leishmania major | histone deacetylase, putative | 0.0517 | 1 | 1 |
Entamoeba histolytica | histone deacetylase, putative | 0.0517 | 1 | 0.5 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0394 | 0.7053 | 0.5753 |
Plasmodium vivax | histone deacetylase 2, putative | 0.0394 | 0.7053 | 0.5753 |
Trypanosoma brucei | histone deacetylase 3 | 0.0394 | 0.7053 | 0.5753 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.1807 | 0.1744 |
Echinococcus multilocularis | insulin receptor | 0.0101 | 0.0076 | 0.0076 |
Echinococcus multilocularis | histone deacetylase 6 | 0.04 | 0.7215 | 0.7215 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0171 | 0.1727 | 0.1727 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0317 | 0.5234 | 0.5234 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.0517 | 1 | 1 |
Plasmodium vivax | histone deacetylase 1, putative | 0.0517 | 1 | 1 |
Brugia malayi | Histone deacetylase family protein | 0.0394 | 0.7053 | 0.7031 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0517 | 1 | 0.5 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0517 | 1 | 0.5 |
Giardia lamblia | Histone deacetylase | 0.0517 | 1 | 0.5 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0517 | 1 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0517 | 1 | 0.5 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.0394 | 0.7053 | 0.5753 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.0394 | 0.7053 | 0.7031 |
Brugia malayi | histone deacetylase 11 | 0.0226 | 0.3062 | 0.3008 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0517 | 1 | 0.5 |
Plasmodium vivax | histone deacetylase, putative | 0.0394 | 0.7053 | 0.5753 |
Echinococcus granulosus | histone deacetylase 6 | 0.0394 | 0.7053 | 0.7031 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0394 | 0.7053 | 0.7031 |
Schistosoma mansoni | tyrosine kinase | 0.0171 | 0.1727 | 0.1663 |
Leishmania major | histone deacetylase, putative | 0.0517 | 1 | 1 |
Loa Loa (eye worm) | histone deacetylase | 0.0394 | 0.7053 | 0.7031 |
Loa Loa (eye worm) | hypothetical protein | 0.0517 | 1 | 1 |
Brugia malayi | Histone deacetylase 1 | 0.0517 | 1 | 1 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0317 | 0.5234 | 0.5198 |
Echinococcus multilocularis | histone deacetylase 8 | 0.0226 | 0.3062 | 0.3062 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.0517 | 1 | 1 |
Echinococcus granulosus | histone deacetylase | 0.0394 | 0.7053 | 0.7031 |
Schistosoma mansoni | tyrosine kinase | 0.0171 | 0.1727 | 0.1663 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0171 | 0.1727 | 0.1663 |
Echinococcus granulosus | histone deacetylase 7 | 0.0394 | 0.7053 | 0.7031 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0517 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0517 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0169 | 0.1684 | 0.162 |
Echinococcus granulosus | histone deacetylase 8 | 0.0226 | 0.3062 | 0.3008 |
Echinococcus granulosus | histone deacetylase 6 | 0.04 | 0.7215 | 0.7193 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0317 | 0.5234 | 0.5198 |
Schistosoma mansoni | histone deacetylase hda2 | 0.04 | 0.7215 | 0.7193 |
Echinococcus granulosus | histone deacetylase 1 | 0.0517 | 1 | 1 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0101 | 0.0076 | 0.0076 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0517 | 1 | 0.5 |
Echinococcus multilocularis | histone deacetylase | 0.0394 | 0.7053 | 0.7053 |
Trypanosoma brucei | histone deacetylase 4 | 0.0394 | 0.7053 | 0.5753 |
Schistosoma mansoni | tyrosine kinase | 0.0317 | 0.5234 | 0.5198 |
Loa Loa (eye worm) | hypothetical protein | 0.0226 | 0.3062 | 0.3008 |
Schistosoma mansoni | histone deacetylase | 0.0517 | 1 | 1 |
Onchocerca volvulus | Histone deacetylase 10 homolog | 0.0226 | 0.3062 | 0.5 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.0517 | 1 | 1 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0394 | 0.7053 | 0.5753 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0394 | 0.7053 | 0.5753 |
Schistosoma mansoni | histone deacetylase 1 2 3 | 0.0226 | 0.3062 | 0.3008 |
Schistosoma mansoni | histone deacetylase | 0.0517 | 1 | 1 |
Trypanosoma brucei | histone deacetylase 1 | 0.0517 | 1 | 1 |
Loa Loa (eye worm) | histone deacetylase 11 | 0.0226 | 0.3062 | 0.3008 |
Plasmodium falciparum | histone deacetylase 1 | 0.0517 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0169 | 0.1684 | 0.162 |
Echinococcus multilocularis | histone deacetylase 3 | 0.0517 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0394 | 0.7053 | 0.7053 |
Echinococcus multilocularis | histone deacetylase 1 | 0.0517 | 1 | 1 |
Echinococcus granulosus | histone deacetylase 6 | 0.0394 | 0.7053 | 0.7031 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0226 | 0.3062 | 0.3008 |
Trypanosoma brucei | histone deacetylase, putative | 0.0394 | 0.7053 | 0.5753 |
Echinococcus granulosus | histone deacetylase 3 | 0.0517 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase 7 | 0.0394 | 0.7053 | 0.7053 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0317 | 0.5234 | 0.5198 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.