Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0407 | 1 | 1 |
Onchocerca volvulus | 0.0407 | 1 | 1 | |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0407 | 1 | 1 |
Echinococcus multilocularis | transmembrane protease serine 3 | 0.0407 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0407 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0407 | 1 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0407 | 1 | 0.5 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0407 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0407 | 1 | 1 |
Echinococcus granulosus | subfamily S1A unassigned peptidase S01 family | 0.0407 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0407 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0407 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0407 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.0962 | 0.0962 |
Echinococcus multilocularis | glycoprotein Antigen 5 | 0.0407 | 1 | 1 |
Brugia malayi | Trypsin family protein | 0.0407 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0407 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0407 | 1 | 1 |
Echinococcus granulosus | Peptidase S1 S6 chymotrypsin Hap | 0.0407 | 1 | 1 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0407 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0407 | 1 | 1 |
Onchocerca volvulus | 0.0407 | 1 | 1 | |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0317 | 0.6879 | 0.6547 |
Loa Loa (eye worm) | hypothetical protein | 0.0407 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0407 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0407 | 1 | 1 |
Echinococcus granulosus | Mastin | 0.0407 | 1 | 1 |
Echinococcus multilocularis | Mastin | 0.0407 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0407 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0407 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0407 | 1 | 1 |
Onchocerca volvulus | 0.0407 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.0962 | 0.0962 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0317 | 0.6879 | 0.6879 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0407 | 1 | 1 |
Onchocerca volvulus | 0.0407 | 1 | 1 | |
Brugia malayi | Trypsin-like protease protein 5 | 0.0407 | 1 | 1 |
Brugia malayi | Trypsin family protein | 0.0407 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0407 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0407 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0407 | 1 | 1 |
Echinococcus multilocularis | Peptidase S1 S6, chymotrypsin Hap | 0.0407 | 1 | 1 |
Echinococcus granulosus | transmembrane protease serine 3 | 0.0407 | 1 | 1 |
Echinococcus multilocularis | enteropeptidase | 0.0407 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0407 | 1 | 1 |
Brugia malayi | Trypsin family protein | 0.0407 | 1 | 1 |
Echinococcus multilocularis | subfamily S1A unassigned peptidase (S01 family) | 0.0407 | 1 | 1 |
Echinococcus granulosus | enteropeptidase | 0.0407 | 1 | 1 |
Onchocerca volvulus | Putative nachr subunit | 0.0317 | 0.6879 | 0.6547 |
Loa Loa (eye worm) | hypothetical protein | 0.0407 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0407 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0407 | 1 | 1 |
Loa Loa (eye worm) | trypsin family protein | 0.0407 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0407 | 1 | 1 |
Onchocerca volvulus | 0.0407 | 1 | 1 | |
Echinococcus granulosus | glycoprotein Antigen 5 | 0.0407 | 1 | 1 |
Onchocerca volvulus | 0.0407 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0317 | 0.6879 | 0.6879 |
Brugia malayi | Chymotrypsin-like protease CTRL-1 precursor | 0.0407 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0407 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.