Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | epidermal growth factor receptor | 0.0255 | 0.2256 | 0.2256 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0474 | 0.684 | 1 |
Echinococcus multilocularis | insulin receptor | 0.0151 | 0.0099 | 0.0099 |
Echinococcus multilocularis | high affinity choline transporter 1 | 0.0159 | 0.0268 | 0.0268 |
Schistosoma mansoni | inositol transporter | 0.0625 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.0268 | 0.025 |
Schistosoma mansoni | high-affinity choline transporter | 0.0159 | 0.0268 | 0.017 |
Schistosoma mansoni | tyrosine kinase | 0.0474 | 0.684 | 0.6808 |
Schistosoma mansoni | tyrosine kinase | 0.0252 | 0.22 | 0.2122 |
Schistosoma mansoni | inositol transporter | 0.0625 | 1 | 1 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0474 | 0.684 | 1 |
Echinococcus multilocularis | solute carrier family 5 | 0.0625 | 1 | 1 |
Echinococcus granulosus | high affinity choline transporter 1 | 0.0159 | 0.0268 | 0.017 |
Echinococcus multilocularis | sodium:myo inositol cotransporter | 0.0625 | 1 | 1 |
Brugia malayi | Sodium:solute symporter family protein | 0.0159 | 0.0268 | 0.025 |
Echinococcus multilocularis | sodium:glucose cotransporter 2 | 0.0625 | 1 | 1 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0255 | 0.2256 | 0.2179 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.0268 | 0.025 |
Schistosoma mansoni | tyrosine kinase | 0.0255 | 0.2256 | 0.2179 |
Schistosoma mansoni | tyrosine kinase | 0.0252 | 0.22 | 0.2122 |
Schistosoma mansoni | tyrosine kinase | 0.0252 | 0.22 | 0.2122 |
Onchocerca volvulus | 0.0159 | 0.0268 | 0.5 | |
Schistosoma mansoni | tyrosine kinase | 0.0255 | 0.2256 | 0.2179 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0255 | 0.2256 | 0.2179 |
Brugia malayi | GH02984p | 0.0159 | 0.0268 | 0.025 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0474 | 0.684 | 0.684 |
Echinococcus granulosus | sodium:glucose cotransporter 2 | 0.0625 | 1 | 1 |
Echinococcus granulosus | solute carrier family 5 | 0.0625 | 1 | 1 |
Echinococcus granulosus | sodium coupled monocarboxylate transporter 1 | 0.0159 | 0.0268 | 0.017 |
Echinococcus multilocularis | sodium coupled monocarboxylate transporter 1 | 0.0159 | 0.0268 | 0.0268 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0151 | 0.0099 | 0.0099 |
Schistosoma mansoni | sodium/solute symporter | 0.0159 | 0.0268 | 0.017 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0474 | 0.684 | 0.6808 |
Echinococcus granulosus | sodium:myo inositol cotransporter | 0.0625 | 1 | 1 |
Toxoplasma gondii | transporter, solute:sodium symporter (SSS) family protein | 0.0159 | 0.0268 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.