Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | cyclin family protein | 0.0415 | 0.0187 | 0.1835 |
Entamoeba histolytica | cyclin, putative | 0.0415 | 0.0187 | 0.1835 |
Trichomonas vaginalis | cyclin B, putative | 0.0415 | 0.0187 | 0.1835 |
Echinococcus multilocularis | G2:mitotic specific cyclin B3 | 0.0415 | 0.0187 | 0.0354 |
Loa Loa (eye worm) | hypothetical protein | 0.1382 | 0.3671 | 0.3671 |
Schistosoma mansoni | cyclin B | 0.0573 | 0.0757 | 0.0702 |
Trichomonas vaginalis | cyclins, putative | 0.0573 | 0.0757 | 1 |
Trichomonas vaginalis | cyclins, putative | 0.0573 | 0.0757 | 1 |
Schistosoma mansoni | cyclins | 0.0415 | 0.0187 | 0.0129 |
Leishmania major | cyclin | 0.0573 | 0.0757 | 1 |
Trypanosoma cruzi | cyclin, putative | 0.0573 | 0.0757 | 1 |
Trypanosoma cruzi | cyclin 6, putative | 0.0573 | 0.0757 | 1 |
Toxoplasma gondii | cell-cycle-associated protein kinase CDK, putative | 0.0379 | 0.0059 | 0.5 |
Echinococcus multilocularis | cyclins | 0.0415 | 0.0187 | 0.0354 |
Echinococcus granulosus | G1:S specific cyclin D1 | 0.1382 | 0.3671 | 1 |
Echinococcus multilocularis | cyclins | 0.0415 | 0.0187 | 0.0354 |
Giardia lamblia | G2/mitotic-specific cyclin B | 0.0573 | 0.0757 | 1 |
Echinococcus granulosus | cyclins | 0.0415 | 0.0187 | 0.0354 |
Echinococcus granulosus | cyclins | 0.0415 | 0.0187 | 0.0354 |
Echinococcus multilocularis | cyclin B3 1 | 0.0415 | 0.0187 | 0.0354 |
Echinococcus multilocularis | cyclins | 0.0415 | 0.0187 | 0.0354 |
Echinococcus granulosus | cyclin B | 0.0573 | 0.0757 | 0.1932 |
Schistosoma mansoni | serine/threonine protein kinase | 0.3139 | 1 | 1 |
Trypanosoma cruzi | CYC2-like cyclin, putative | 0.0573 | 0.0757 | 1 |
Leishmania major | CYC2-like cyclin, putative,cyclin 6, putative | 0.0573 | 0.0757 | 1 |
Echinococcus multilocularis | cyclins | 0.0415 | 0.0187 | 0.0354 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0415 | 0.0187 | 0.1835 |
Schistosoma mansoni | cyclin d | 0.1382 | 0.3671 | 0.3633 |
Echinococcus granulosus | cyclins | 0.0415 | 0.0187 | 0.0354 |
Giardia lamblia | Cyclin A | 0.0415 | 0.0187 | 0.1835 |
Echinococcus multilocularis | cyclin b3 | 0.0415 | 0.0187 | 0.0354 |
Onchocerca volvulus | 0.0573 | 0.0757 | 0.5 | |
Trichomonas vaginalis | cyclin A, putative | 0.0573 | 0.0757 | 1 |
Trypanosoma cruzi | cyclin, putative | 0.0573 | 0.0757 | 1 |
Echinococcus multilocularis | cyclins | 0.0415 | 0.0187 | 0.0354 |
Loa Loa (eye worm) | CMGC/CDK/CDK5 protein kinase | 0.0379 | 0.0059 | 0.0059 |
Trichomonas vaginalis | cyclins, putative | 0.0573 | 0.0757 | 1 |
Plasmodium vivax | protein kinase Crk2 | 0.0379 | 0.0059 | 0.5 |
Echinococcus granulosus | cyclin B3 1 | 0.0415 | 0.0187 | 0.0354 |
Schistosoma mansoni | cyclin B3 | 0.0415 | 0.0187 | 0.0129 |
Entamoeba histolytica | cyclin family protein | 0.0415 | 0.0187 | 0.1835 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.1382 | 0.3671 | 0.3633 |
Echinococcus granulosus | cyclins | 0.0415 | 0.0187 | 0.0354 |
Trichomonas vaginalis | cyclins, putative | 0.0415 | 0.0187 | 0.1835 |
Loa Loa (eye worm) | CAMK/CAMKL/CHK1 protein kinase | 0.3139 | 1 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0573 | 0.0757 | 1 |
Plasmodium falciparum | cyclin | 0.0415 | 0.0187 | 1 |
Echinococcus granulosus | cyclin b3 | 0.0415 | 0.0187 | 0.0354 |
Trichomonas vaginalis | cyclin D, putative | 0.0415 | 0.0187 | 0.1835 |
Echinococcus multilocularis | cyclins | 0.0415 | 0.0187 | 0.0354 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0379 | 0.0059 | 0.0059 |
Loa Loa (eye worm) | hypothetical protein | 0.1282 | 0.3311 | 0.3311 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0415 | 0.0187 | 0.0129 |
Trichomonas vaginalis | cyclin B, putative | 0.0573 | 0.0757 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0573 | 0.0757 | 0.0757 |
Trichomonas vaginalis | cyclin B3, putative | 0.0415 | 0.0187 | 0.1835 |
Echinococcus multilocularis | cyclin B | 0.0573 | 0.0757 | 0.1932 |
Trypanosoma brucei | mitotic cyclin 6 | 0.0573 | 0.0757 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0573 | 0.0757 | 1 |
Echinococcus multilocularis | cyclins | 0.0415 | 0.0187 | 0.0354 |
Trichomonas vaginalis | cyclin B, putative | 0.0573 | 0.0757 | 1 |
Echinococcus granulosus | cyclins | 0.0415 | 0.0187 | 0.0354 |
Entamoeba histolytica | cyclin, putative | 0.0573 | 0.0757 | 1 |
Trichomonas vaginalis | cyclin D, putative | 0.0415 | 0.0187 | 0.1835 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0415 | 0.0187 | 0.0187 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0379 | 0.0059 | 0.0059 |
Loa Loa (eye worm) | hypothetical protein | 0.0573 | 0.0757 | 0.0757 |
Trichomonas vaginalis | cyclins, putative | 0.0573 | 0.0757 | 1 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0573 | 0.0757 | 0.0702 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0573 | 0.0757 | 0.0702 |
Echinococcus multilocularis | G1:S specific cyclin D1 | 0.1382 | 0.3671 | 1 |
Giardia lamblia | Hypothetical protein | 0.0415 | 0.0187 | 0.1835 |
Echinococcus granulosus | G2:mitotic specific cyclin B3 | 0.0415 | 0.0187 | 0.0354 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.