Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0347 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0644 | 0.0644 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0029 | 0.0332 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0029 | 0.0332 | 0.5 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0332 | 0.2768 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | inward rectifying k channel family protein 1 | 0.0347 | 1 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0058 | 0.1199 | 0.1199 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0332 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.1199 | 0.1199 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0037 | 0.0569 | 0.4745 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0035 | 0.0495 | 0.5 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0029 | 0.0332 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0039 | 0.0644 | 0.5371 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0332 | 0.5 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0037 | 0.0569 | 0.0569 |
Schistosoma mansoni | voltage-gated potassium channel | 0.004 | 0.0672 | 1 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0037 | 0.0569 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.004 | 0.0672 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0644 | 0.9581 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0332 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0332 | 0.5 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0037 | 0.0569 | 1 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0035 | 0.0495 | 0.5 |
Toxoplasma gondii | hypothetical protein | 0.0347 | 1 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0058 | 0.1199 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.042 | 0.042 |
Loa Loa (eye worm) | hypothetical protein | 0.0347 | 1 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0058 | 0.1199 | 1 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0018 | 0.0147 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.