Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | transitional endoplasmic reticulum atpase | 0.025 | 0.3228 | 0.3228 |
Trypanosoma brucei | Valosin-containing protein | 0.0574 | 0.9406 | 0.5 |
Toxoplasma gondii | cell division protein CDC48AP | 0.0362 | 0.5363 | 0.0000097958 |
Loa Loa (eye worm) | hypothetical protein | 0.0355 | 0.5224 | 1 |
Toxoplasma gondii | cell division protein CDC48CY | 0.0606 | 1 | 1 |
Giardia lamblia | AAA family ATPase | 0.0362 | 0.5363 | 0.5 |
Entamoeba histolytica | transitional endoplasmic reticulum ATPase, putative | 0.0574 | 0.9406 | 1 |
Schistosoma mansoni | cell division control protein 48 aaa family protein | 0.025 | 0.3228 | 0.3228 |
Trichomonas vaginalis | spermatogenesis associated factor, putative | 0.0606 | 1 | 1 |
Brugia malayi | valosin containing protein | 0.0355 | 0.5224 | 1 |
Brugia malayi | transitional endoplasmic reticulum ATPase TER94, putative | 0.025 | 0.3228 | 0.6178 |
Trypanosoma cruzi | Valosin-containing protein, putative | 0.0574 | 0.9406 | 0.5 |
Onchocerca volvulus | Transitional endoplasmic reticulum ATPase homolog | 0.0606 | 1 | 0.5 |
Echinococcus multilocularis | transitional endoplasmic reticulum atpase | 0.0606 | 1 | 1 |
Brugia malayi | vesicle-fusing ATPase | 0.0355 | 0.5224 | 1 |
Plasmodium falciparum | cell division cycle protein 48 homologue, putative | 0.0574 | 0.9406 | 0.5 |
Entamoeba histolytica | cdc48-like protein, putative | 0.0574 | 0.9406 | 1 |
Schistosoma mansoni | cell division control protein 48 aaa family protein | 0.0606 | 1 | 1 |
Mycobacterium ulcerans | ATPase | 0.0362 | 0.5363 | 0.5 |
Loa Loa (eye worm) | vesicle-fusing ATPase | 0.0355 | 0.5224 | 1 |
Schistosoma mansoni | cell division control protein 48 aaa family protein | 0.0574 | 0.9406 | 0.9406 |
Mycobacterium tuberculosis | Putative conserved ATPase | 0.0362 | 0.5363 | 0.5 |
Leishmania major | Transitional endoplasmic reticulum ATPase, putative,valosin-containing protein homolog | 0.0574 | 0.9406 | 0.5 |
Plasmodium vivax | cell division cycle protein 48 homologue, putative | 0.0574 | 0.9406 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.