Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | presenilin spe-4 | 0.1192 | 0.3003 | 1 |
Brugia malayi | hypothetical protein | 0.1192 | 0.3003 | 0.3003 |
Brugia malayi | Presenilin-like protein At2g29900 | 0.1192 | 0.3003 | 0.3003 |
Brugia malayi | Presenilin spe-4 | 0.1192 | 0.3003 | 0.3003 |
Brugia malayi | Presenilin spe-4 | 0.1192 | 0.3003 | 0.3003 |
Toxoplasma gondii | hypothetical protein | 0.1192 | 0.3003 | 0.5 |
Brugia malayi | Presenilin spe-4 | 0.1192 | 0.3003 | 0.3003 |
Brugia malayi | hypothetical protein | 0.1192 | 0.3003 | 0.3003 |
Brugia malayi | hypothetical protein | 0.1192 | 0.3003 | 0.3003 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.