Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | casein kinase, putative | 0.1992 | 1 | 1 |
Echinococcus multilocularis | casein kinase I alpha | 0.1992 | 1 | 0.5 |
Leishmania major | casein kinase, putative | 0.1992 | 1 | 0.5 |
Loa Loa (eye worm) | CK1/CK1/CK1-A protein kinase | 0.1992 | 1 | 0.5 |
Entamoeba histolytica | casein kinase, putative | 0.1992 | 1 | 0.5 |
Entamoeba histolytica | casein kinase 1, putative | 0.1992 | 1 | 0.5 |
Trichomonas vaginalis | CK1 family protein kinase | 0.1992 | 1 | 0.5 |
Giardia lamblia | Kinase, CK1 Casein kinase | 0.1992 | 1 | 0.5 |
Plasmodium falciparum | casein kinase 1 | 0.1992 | 1 | 0.5 |
Trypanosoma brucei | casein kinase I, isoform 2 | 0.1992 | 1 | 0.5 |
Echinococcus multilocularis | casein kinase I alpha | 0.1992 | 1 | 0.5 |
Trichomonas vaginalis | CK1 family protein kinase | 0.1992 | 1 | 0.5 |
Trypanosoma cruzi | casein kinase, delta isoform, putative | 0.1992 | 1 | 1 |
Trypanosoma cruzi | casein kinase, putative | 0.1992 | 1 | 1 |
Echinococcus granulosus | casein kinase I delta | 0.1992 | 1 | 0.5 |
Echinococcus multilocularis | casein kinase I alpha | 0.1992 | 1 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1992 | 1 | 0.5 |
Trypanosoma cruzi | casein kinase, putative | 0.1992 | 1 | 1 |
Echinococcus granulosus | casein kinase I alpha | 0.1992 | 1 | 0.5 |
Brugia malayi | casein kinase I | 0.1992 | 1 | 0.5 |
Toxoplasma gondii | casein kinase I | 0.1992 | 1 | 0.5 |
Trichomonas vaginalis | CK1 family protein kinase | 0.1992 | 1 | 0.5 |
Plasmodium vivax | casein kinase 1, putative | 0.1992 | 1 | 0.5 |
Echinococcus granulosus | casein kinase i | 0.1992 | 1 | 0.5 |
Onchocerca volvulus | 0.1992 | 1 | 1 | |
Echinococcus granulosus | casein kinase I alpha | 0.1992 | 1 | 0.5 |
Echinococcus multilocularis | casein kinase I delta | 0.1992 | 1 | 0.5 |
Schistosoma mansoni | protein kinase | 0.1992 | 1 | 0.5 |
Loa Loa (eye worm) | CK1/CK1/CK1-A protein kinase | 0.1992 | 1 | 0.5 |
Trypanosoma cruzi | casein kinase, putative | 0.1992 | 1 | 1 |
Echinococcus multilocularis | casein kinase I delta | 0.1992 | 1 | 0.5 |
Echinococcus granulosus | casein kinase I delta | 0.1992 | 1 | 0.5 |
Loa Loa (eye worm) | CK1/CK1/CK1-D protein kinase | 0.1992 | 1 | 0.5 |
Trypanosoma cruzi | casein kinase, putative | 0.1992 | 1 | 1 |
Echinococcus multilocularis | casein kinase i | 0.1992 | 1 | 0.5 |
Echinococcus granulosus | casein kinase I alpha | 0.1992 | 1 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
NI (binding) | Inhibition of hamster liver aldehyde dehydrogenase ALDH-2; No inhibition microM | ChEMBL. | 11563931 | |
NI (binding) | Inhibition of hamster liver mitochondrial monoamine oxidase MAO | ChEMBL. | 11563931 | |
NI (binding) | 0 | Inhibition of hamster liver aldehyde dehydrogenase ALDH-2; No inhibition microM | ChEMBL. | 11563931 |
NI (binding) | 0 | Inhibition of hamster liver mitochondrial monoamine oxidase MAO | ChEMBL. | 11563931 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.