Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Leucine Rich Repeat family protein | 0.0001 | 0 | 0.5 |
Toxoplasma gondii | leucine-rich repeat protein LRR1 | 0.0001 | 0 | 0.5 |
Onchocerca volvulus | 0.0047 | 0.5071 | 1 | |
Leishmania major | hypothetical protein, conserved | 0.0001 | 0 | 0.5 |
Plasmodium falciparum | leucine-rich repeat protein | 0.0001 | 0 | 0.5 |
Echinococcus multilocularis | leucine rich repeat containing protein 57 | 0.0002 | 0.0021 | 1 |
Plasmodium vivax | protein phosphatases PP1 regulatory subunit sds22, putative | 0.0002 | 0.0021 | 1 |
Trypanosoma cruzi | protein phosphatase 1, regulatory subunit, putative | 0.0002 | 0.0021 | 0.5 |
Echinococcus granulosus | leucine rich repeat containing protein 23 | 0.0001 | 0 | 0.5 |
Trichomonas vaginalis | leucine-rich repeat-containing protein, putative | 0.0002 | 0.0021 | 1 |
Giardia lamblia | Leucine-rich repeat protein | 0.0001 | 0 | 0.5 |
Trichomonas vaginalis | toll, putative | 0.0002 | 0.0021 | 1 |
Brugia malayi | Leucine Rich Repeat family protein | 0.0001 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.