Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hemoglobinase (C13 family) | 0.3143 | 1 | 1 |
Trichomonas vaginalis | Clan CD, family C13, legumain-like cysteine peptidase | 0.3143 | 1 | 0.5 |
Trichomonas vaginalis | Clan CD, family C13, legumain-like cysteine peptidase | 0.3143 | 1 | 0.5 |
Trichomonas vaginalis | Clan CD, family C13, legumain-like cysteine peptidase | 0.3143 | 1 | 0.5 |
Trichomonas vaginalis | Clan CD, family C13, legumain-like cysteine peptidase | 0.3143 | 1 | 0.5 |
Trichomonas vaginalis | Clan CD, family C13, legumain-like cysteine peptidase | 0.3143 | 1 | 0.5 |
Onchocerca volvulus | Legumain homolog | 0.3143 | 1 | 0.5 |
Schistosoma mansoni | hemoglobinase (C13 family) | 0.3143 | 1 | 1 |
Trichomonas vaginalis | Clan CD, family C13, legumain-like cysteine peptidase | 0.3143 | 1 | 0.5 |
Schistosoma mansoni | family C13 non-peptidase homologue (C13 family) | 0.3143 | 1 | 1 |
Trichomonas vaginalis | Clan CD, family C13, legumain-like cysteine peptidase | 0.3143 | 1 | 0.5 |
Loa Loa (eye worm) | peptidase C13 family protein | 0.3143 | 1 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | Antibacterial activity of the compound against Escherichia coli (ATCC NCTC 6571) at a concentration of 200 microg/mL; not active | ChEMBL. | 12565921 | |
Activity (functional) | 0 | Antibacterial activity of the compound against Corynebacterium sp. (ATCC 68984) at a concentration of 200 microg/mL; Active | ChEMBL. | 12565921 |
Activity (functional) | 0 | Antibacterial activity of the compound against Pasteurella sp.(ATCC 67535) at a concentration of 200 microg/mL; Active | ChEMBL. | 12565921 |
Activity (functional) | 0 | Antibacterial activity of the compound against Pasteurella sp.(ATCC 67777) at a concentration of 200 microg/mL; not active | ChEMBL. | 12565921 |
Activity (functional) | 0 | Antibacterial activity of the compound against Pasteurella sp.(ATCC 69527) at a concentration of 200 microg/mL; not active | ChEMBL. | 12565921 |
Activity (functional) | 0 | Antibacterial activity of the compound against Pasteurella sp.(ATCC 71886) at a concentration of 200 microg/mL; not active | ChEMBL. | 12565921 |
Activity (functional) | 0 | Antibacterial activity of the compound against Pasteurella multocida (ATCC 61096) at a concentration of 200 microg/mL; not active | ChEMBL. | 12565921 |
Activity (functional) | 0 | Antibacterial activity of the compound against Pasteurella multocida (ATCC 63560) at a concentration of 200 microg/mL; not active | ChEMBL. | 12565921 |
Activity (functional) | 0 | Antibacterial activity of the compound against Actinomyces meyeri (ATCC 61789) at a concentration of 200 microg/mL; Active | ChEMBL. | 12565921 |
Activity (functional) | 0 | Antibacterial activity of the compound against Actinomyces sp.(ATCC 70710) at a concentration of 200 microg/mL; Active | ChEMBL. | 12565921 |
Activity (functional) | 0 | Antibacterial activity of the compound against Bacteroides bivus (ATCC 64362) at a concentration of 200 microg/mL; not active | ChEMBL. | 12565921 |
Activity (functional) | 0 | Antibacterial activity of the compound against Bacteroides buccae (ATCC 67792) at a concentration of 200 microg/mL; not active | ChEMBL. | 12565921 |
Activity (functional) | 0 | Antibacterial activity of the compound against Bacteroides capillosus (ATCC 60802) at a concentration of 200 microg/mL; not active | ChEMBL. | 12565921 |
Activity (functional) | 0 | Antibacterial activity of the compound against Bacteroides oralis (ATCC 72708) at a concentration of 200 microg/mL; not active | ChEMBL. | 12565921 |
Activity (functional) | 0 | Antibacterial activity of the compound against Bacteroides ovatus (ATCC 66640) at a concentration of 200 microg/mL; not active | ChEMBL. | 12565921 |
Activity (functional) | 0 | Antibacterial activity of the compound against Bacteroides uniformis (ATCC 62723) at a concentration of 200 microg/mL; not active | ChEMBL. | 12565921 |
Activity (functional) | 0 | Antibacterial activity of the compound against Fusobacterium mortiferum (ATCC 63425) at a concentration of 200 microg/mL; not active | ChEMBL. | 12565921 |
Activity (functional) | 0 | Antibacterial activity of the compound against Fusobacterium sp.(ATCC 74714) at a concentration of 200 microg/mL; not active | ChEMBL. | 12565921 |
Activity (functional) | 0 | Antibacterial activity of the compound against Propionibacterium sp.(ATCC 72661) at a concentration of 200 microg/mL; Active | ChEMBL. | 12565921 |
Activity (functional) | NA 0 | Antibacterial activity of the compound against Porphyromonas gingivalis sp.(ATCC D23C) at a concentration of 200 microg/mL | ChEMBL. | 12565921 |
Activity (functional) | 0 | Antibacterial activity of the compound against Porphyromonas canoris (ATCC NCTC 12835) at a concentration of 200 microg/mL; Active | ChEMBL. | 12565921 |
Activity (functional) | 0 | Antibacterial activity of the compound against Porphyromonas canoris (ATCC NCTC 12836) at a concentration of 200 microg/mL; Active | ChEMBL. | 12565921 |
Activity (functional) | 0 | Antibacterial activity of the compound against Escherichia coli (ATCC NCTC 6571) at a concentration of 200 microg/mL; not active | ChEMBL. | 12565921 |
Activity (functional) | 0 | Antibacterial activity of the compound against Staphylococcus aureus (ATCC NCTC 6571) at a concentration of 200 microg/mL; not active | ChEMBL. | 12565921 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.