Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0164 | 0.0164 |
Mycobacterium ulcerans | hypothetical protein | 0.0145 | 0.3235 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0 | 0.5 |
Trichomonas vaginalis | esterase, putative | 0.0038 | 0 | 0.5 |
Echinococcus granulosus | snurportin 1 | 0.0326 | 0.8682 | 1 |
Mycobacterium leprae | Probable lipase LipE | 0.0038 | 0 | 0.5 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0326 | 0.8682 | 0.8682 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0 | 0.5 |
Plasmodium vivax | hypothetical protein, conserved | 0.0038 | 0 | 0.5 |
Leishmania major | C-8 sterol isomerase-like protein | 0.037 | 1 | 1 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.017 | 0.3964 | 0.4566 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.0057 | 0.0569 | 0.0569 |
Treponema pallidum | mcbG protein | 0.0145 | 0.3235 | 0.5 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.017 | 0.3964 | 0.4566 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.0057 | 0.0569 | 0.0569 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.017 | 0.3964 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0145 | 0.3235 | 0.3235 |
Loa Loa (eye worm) | hypothetical protein | 0.037 | 1 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0057 | 0.0569 | 0.0569 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0 | 0.5 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.0057 | 0.0569 | 1 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.0057 | 0.0569 | 0.0656 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.017 | 0.3964 | 0.4566 |
Echinococcus multilocularis | snurportin 1 | 0.0326 | 0.8682 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0145 | 0.3235 | 0.5221 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.0057 | 0.0569 | 0.0569 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.037 | 1 | 1 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.0057 | 0.0569 | 0.0656 |
Leishmania major | hypothetical protein, conserved | 0.0145 | 0.3235 | 0.3235 |
Brugia malayi | RNA, U transporter 1 | 0.0087 | 0.1469 | 0.1469 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0 | 0.5 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.0057 | 0.0569 | 0.0656 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.0057 | 0.0569 | 0.0569 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0145 | 0.3235 | 0.5 |
Brugia malayi | prolyl oligopeptidase family protein | 0.017 | 0.3964 | 0.3964 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.0057 | 0.0569 | 0.0569 |
Schistosoma mansoni | hypothetical protein | 0.0326 | 0.8682 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0189 | 0.4549 | 0.4549 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0244 | 0.6197 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0145 | 0.3235 | 0.3235 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.017 | 0.3964 | 0.3964 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.037 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0044 | 0.0164 | 0.0164 |
Mycobacterium leprae | conserved hypothetical protein | 0.0038 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0145 | 0.3235 | 0.3235 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.