Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Relative SEAP activity (functional) | = 98 % | Compound was tested for human telomerase reverse transcriptase-SEAP (hTERT-SEAP) activity in non-small cell lung cancer H1299 cell at 2.1 microM concentration | ChEMBL. | 12852760 |
Relative SEAP activity (functional) | = 98 % | Compound was tested for human telomerase reverse transcriptase-SEAP (hTERT-SEAP) activity in non-small cell lung cancer H1299 cell at 2.1 microM concentration | ChEMBL. | 12852760 |
Relative SEAP activity (functional) | = 100 % | Compound was tested for human telomerase reverse transcriptase-SEAP (hTERT-SEAP) activity in immortalized hTERT-BJI at 210.0 microM concentration | ChEMBL. | 12852760 |
Relative SEAP activity (functional) | = 100 % | Compound was tested for human telomerase reverse transcriptase-SEAP (hTERT-SEAP) activity in immortalized hTERT-BJI at 210.0 microM concentration | ChEMBL. | 12852760 |
Relative SEAP activity (functional) | = 101 % | Compound was tested for human telomerase reverse transcriptase-SEAP (hTERT-SEAP) activity in non-small cell lung cancer H1299 cell at 21 microM concentration | ChEMBL. | 12852760 |
Relative SEAP activity (functional) | = 101 % | Compound was tested for human telomerase reverse transcriptase-SEAP (hTERT-SEAP) activity in non-small cell lung cancer H1299 cell at 21 microM concentration | ChEMBL. | 12852760 |
Relative SEAP activity (functional) | = 125 % | Compound was tested for human telomerase reverse transcriptase-SEAP (hTERT-SEAP) activity in immortalized hTERT-BJI at 21 microM concentration | ChEMBL. | 12852760 |
Relative SEAP activity (functional) | = 125 % | Compound was tested for human telomerase reverse transcriptase-SEAP (hTERT-SEAP) activity in immortalized hTERT-BJI at 21 microM concentration | ChEMBL. | 12852760 |
Relative SEAP activity (functional) | = 129 % | Compound was tested for human telomerase reverse transcriptase-SEAP (hTERT-SEAP) activity in immortalized hTERT-BJI at 2.1 microM concentration | ChEMBL. | 12852760 |
Relative SEAP activity (functional) | = 129 % | Compound was tested for human telomerase reverse transcriptase-SEAP (hTERT-SEAP) activity in immortalized hTERT-BJI at 2.1 microM concentration | ChEMBL. | 12852760 |
Relative SEAP activity (functional) | = 142 % | Compound was tested for human telomerase reverse transcriptase-SEAP (hTERT-SEAP) activity in non-small cell lung cancer H1299 cell at 210.0 microM concentration | ChEMBL. | 12852760 |
Relative SEAP activity (functional) | = 142 % | Compound was tested for human telomerase reverse transcriptase-SEAP (hTERT-SEAP) activity in non-small cell lung cancer H1299 cell at 210.0 microM concentration | ChEMBL. | 12852760 |
Relative viability (functional) | = 30 % | hTERT-SEAP (Human telomerase reverse transcriptase-SEAP) activity in non-small cell lung cancer H1299 cell at 210.0 microM concentration and level of cell viability determined in MTT assay | ChEMBL. | 12852760 |
Relative viability (functional) | = 30 % | hTERT-SEAP (Human telomerase reverse transcriptase-SEAP) activity in non-small cell lung cancer H1299 cell at 210.0 microM concentration and level of cell viability determined in MTT assay | ChEMBL. | 12852760 |
Relative viability (functional) | = 53 % | hTERT-SEAP (Human telomerase reverse transcriptase-SEAP) activity in non-small cell lung cancer H1299 cell at 21 microM concentration and level of cell viability determined in MTT assay | ChEMBL. | 12852760 |
Relative viability (functional) | = 53 % | hTERT-SEAP (Human telomerase reverse transcriptase-SEAP) activity in non-small cell lung cancer H1299 cell at 21 microM concentration and level of cell viability determined in MTT assay | ChEMBL. | 12852760 |
Relative viability (functional) | = 64 % | hTERT-SEAP (Human telomerase reverse transcriptase-SEAP) activity in immortalized hTERT-BJI at 210.0 microM concentration and level of cell viability determined in MTT assay | ChEMBL. | 12852760 |
Relative viability (functional) | = 64 % | hTERT-SEAP (Human telomerase reverse transcriptase-SEAP) activity in immortalized hTERT-BJI at 210.0 microM concentration and level of cell viability determined in MTT assay | ChEMBL. | 12852760 |
Relative viability (functional) | = 91 % | hTERT-SEAP (Human telomerase reverse transcriptase-SEAP) activity in non-small cell lung cancer H1299 cell at 2.1 microM concentration and level of cell viability determined in MTT assay | ChEMBL. | 12852760 |
Relative viability (functional) | = 91 % | hTERT-SEAP (Human telomerase reverse transcriptase-SEAP) activity in non-small cell lung cancer H1299 cell at 2.1 microM concentration and level of cell viability determined in MTT assay | ChEMBL. | 12852760 |
Relative viability (functional) | = 97 % | hTERT-SEAP (Human telomerase reverse transcriptase-SEAP) activity in immortalized hTERT-BJI at 21 microM concentration and level of cell viability determined in MTT assay | ChEMBL. | 12852760 |
Relative viability (functional) | = 97 % | hTERT-SEAP (Human telomerase reverse transcriptase-SEAP) activity in immortalized hTERT-BJI at 21 microM concentration and level of cell viability determined in MTT assay | ChEMBL. | 12852760 |
Relative viability (functional) | = 106 % | hTERT-SEAP (Human telomerase reverse transcriptase-SEAP) activity in immortalized hTERT-BJI at 2.4 microM concentration and level of cell viability determined in MTT assay | ChEMBL. | 12852760 |
Relative viability (functional) | = 106 % | hTERT-SEAP (Human telomerase reverse transcriptase-SEAP) activity in immortalized hTERT-BJI at 2.4 microM concentration and level of cell viability determined in MTT assay | ChEMBL. | 12852760 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.