Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | brg-1 associated factor | 0.0013 | 0.226 | 0.226 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 1 | 1 |
Loa Loa (eye worm) | brahma associated protein | 0.0013 | 0.226 | 0.226 |
Onchocerca volvulus | Bile acid receptor homolog | 0.002 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 1 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 1 | 1 |
Plasmodium vivax | SWIB/MDM2 domain-containing protein, putative | 0.0013 | 0.226 | 0.5 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.002 | 1 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 1 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 1 | 1 |
Brugia malayi | brahma associated protein 60 kDa | 0.0013 | 0.226 | 0.226 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 1 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.226 | 0.226 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 1 | 1 |
Chlamydia trachomatis | SWIB complex protein | 0.0013 | 0.226 | 0.5 |
Echinococcus granulosus | Upstream activation factor subunit UAF30 | 0.0013 | 0.226 | 0.226 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.226 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 1 | 1 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0013 | 0.226 | 0.226 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 1 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 1 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 1 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 1 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 1 | 1 |
Brugia malayi | steroid hormone receptor | 0.002 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 1 | 1 |
Echinococcus multilocularis | Upstream activation factor subunit UAF30 | 0.0013 | 0.226 | 0.226 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 1 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 1 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 1 | 1 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0013 | 0.226 | 0.5 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.0013 | 0.226 | 0.5 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 1 | 1 |
Brugia malayi | nuclear hormone receptor | 0.002 | 1 | 1 |
Brugia malayi | SWIB/MDM2 domain containing protein | 0.0013 | 0.226 | 0.226 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 1 | 1 |
Brugia malayi | brahma associated protein 60 kDa | 0.0013 | 0.226 | 0.226 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 1 | 1 |
Onchocerca volvulus | 0.002 | 1 | 1 | |
Schistosoma mansoni | coup transcription factor | 0.002 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.226 | 0.226 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 1 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.002 | 1 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 1 | 1 |
Loa Loa (eye worm) | SWIB/MDM2 domain-containing protein | 0.0013 | 0.226 | 0.226 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 1 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0013 | 0.226 | 0.5 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 1 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 1 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.002 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 1 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 1 | 1 |
Echinococcus granulosus | SWI:SNF matrix associated | 0.0013 | 0.226 | 0.226 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 1 | 1 |
Toxoplasma gondii | SWIB/MDM2 domain-containing protein | 0.0013 | 0.226 | 0.5 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0013 | 0.226 | 0.226 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 1 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 1 | 1 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0013 | 0.226 | 0.226 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 1 | 1 |
Chlamydia trachomatis | DNA topoisomerase I | 0.0013 | 0.226 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.226 | 0.226 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 1 | 1 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0013 | 0.226 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.