Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | selectin P (granule membrane protein 140kDa, antigen CD62) | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | ATPase | 0.0343 | 0.5767 | 0.5 |
Giardia lamblia | AAA family ATPase | 0.0343 | 0.5767 | 1 |
Trypanosoma cruzi | Valosin-containing protein, putative | 0.0544 | 0.9457 | 1 |
Trichomonas vaginalis | proteasome-activating nucleotidase, putative | 0.0136 | 0.195 | 0.195 |
Plasmodium falciparum | cell division cycle protein 48 homologue, putative | 0.0544 | 0.9457 | 1 |
Plasmodium vivax | cell division cycle protein 48 homologue, putative | 0.0544 | 0.9457 | 1 |
Mycobacterium tuberculosis | Putative conserved ATPase | 0.0343 | 0.5767 | 0.5 |
Entamoeba histolytica | cdc48-like protein, putative | 0.0544 | 0.9457 | 1 |
Schistosoma mansoni | cell division control protein 48 aaa family protein | 0.0574 | 1 | 1 |
Schistosoma mansoni | cell division control protein 48 aaa family protein | 0.0544 | 0.9457 | 0.9457 |
Loa Loa (eye worm) | vesicle-fusing ATPase | 0.0336 | 0.564 | 1 |
Echinococcus multilocularis | transitional endoplasmic reticulum atpase | 0.0574 | 1 | 1 |
Brugia malayi | vesicle-fusing ATPase | 0.0336 | 0.564 | 1 |
Trichomonas vaginalis | 26S protease regulatory subunit S10b, putative | 0.0136 | 0.195 | 0.195 |
Loa Loa (eye worm) | hypothetical protein | 0.0336 | 0.564 | 1 |
Trichomonas vaginalis | spermatogenesis associated factor, putative | 0.0574 | 1 | 1 |
Brugia malayi | transitional endoplasmic reticulum ATPase TER94, putative | 0.0237 | 0.3817 | 0.6768 |
Onchocerca volvulus | Transitional endoplasmic reticulum ATPase homolog | 0.0574 | 1 | 0.5 |
Leishmania major | Transitional endoplasmic reticulum ATPase, putative,valosin-containing protein homolog | 0.0544 | 0.9457 | 1 |
Brugia malayi | valosin containing protein | 0.0336 | 0.564 | 1 |
Trypanosoma brucei | Valosin-containing protein | 0.0544 | 0.9457 | 1 |
Loa Loa (eye worm) | VCP protein | 0.0237 | 0.3817 | 0.6768 |
Toxoplasma gondii | cell division protein CDC48AP | 0.0343 | 0.5767 | 0.5767 |
Schistosoma mansoni | cell division control protein 48 aaa family protein | 0.0237 | 0.3817 | 0.3817 |
Echinococcus multilocularis | transitional endoplasmic reticulum atpase | 0.0237 | 0.3817 | 0.3817 |
Entamoeba histolytica | transitional endoplasmic reticulum ATPase, putative | 0.0544 | 0.9457 | 1 |
Toxoplasma gondii | transitional endoplasmic reticulum ATPase, putative | 0.0343 | 0.5767 | 0.5767 |
Toxoplasma gondii | cell division protein CDC48CY | 0.0574 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 0.1 uM | In vitro inhibitory concentration against Selectin P in a cell-free binding assay | ChEMBL. | 9379443 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.