Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0078 | 0.1302 | 0.311 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0041 | 0 | 0.5 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0078 | 0.1302 | 1 |
Toxoplasma gondii | NAC domain-containing protein | 0.0041 | 0 | 0.5 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0078 | 0.1302 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.4188 | 0.4188 |
Trichomonas vaginalis | glutaminase, putative | 0.0322 | 1 | 1 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0078 | 0.1302 | 1 |
Mycobacterium ulcerans | glutaminase | 0.0322 | 1 | 0.5 |
Schistosoma mansoni | eukaryotic translation initiation factor 4h | 0.0159 | 0.4188 | 0.4188 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0045 | 0.0136 | 0.0325 |
Loa Loa (eye worm) | glutaminase 2 | 0.0322 | 1 | 1 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0078 | 0.1302 | 0.1302 |
Echinococcus granulosus | Eukaryotic translation initiation factor 4H | 0.0159 | 0.4188 | 1 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0078 | 0.1302 | 0.311 |
Loa Loa (eye worm) | glutaminase | 0.0322 | 1 | 1 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0045 | 0.0136 | 0.0325 |
Echinococcus multilocularis | Eukaryotic translation initiation factor 4H | 0.0159 | 0.4188 | 1 |
Schistosoma mansoni | eukaryotic translation initiation factor 4h | 0.0159 | 0.4188 | 0.4188 |
Schistosoma mansoni | eukaryotic translation initiation factor 4h | 0.0159 | 0.4188 | 0.4188 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0078 | 0.1302 | 0.1302 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0041 | 0 | 0.5 |
Brugia malayi | RNA binding protein | 0.0159 | 0.4188 | 0.4188 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0078 | 0.1302 | 1 |
Schistosoma mansoni | glutaminase | 0.0322 | 1 | 1 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0078 | 0.1302 | 0.1302 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0078 | 0.1302 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.