Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Loa Loa (eye worm) | glutamate receptor | 0.0039 | 0.0677 | 0.0765 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0033 | 0.0485 | 0.0485 |
Loa Loa (eye worm) | hypothetical protein | 0.0138 | 0.3676 | 0.4154 |
Schistosoma mansoni | hypothetical protein | 0.031 | 0.8851 | 0.8851 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0017 | 0 | 0.5 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0017 | 0 | 0.5 |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0035 | 0.0566 | 0.836 |
Echinococcus granulosus | metabotropic glutamate receptor 2 | 0.0033 | 0.0485 | 0.0548 |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Echinococcus granulosus | small conductance calcium activated potassium | 0.031 | 0.8851 | 1 |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Echinococcus multilocularis | metabotropic glutamate receptor 2 | 0.0033 | 0.0485 | 0.0548 |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Echinococcus multilocularis | small conductance calcium activated potassium | 0.031 | 0.8851 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.031 | 0.8851 | 1 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0295 | 0.8394 | 0.8394 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.3705 | 0.4186 |
Schistosoma mansoni | calcium-activated potassium channel | 0.031 | 0.8851 | 0.8851 |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.0048 | 0.095 | 0.1073 |
Echinococcus multilocularis | serotonin receptor | 0.0138 | 0.3676 | 0.4154 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.0048 | 0.095 | 0.1073 |
Echinococcus multilocularis | serotonin receptor | 0.0138 | 0.3676 | 0.4154 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0138 | 0.3676 | 0.3676 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0019 | 0.0072 | 0.0072 |
Brugia malayi | metabotropic glutamate receptor type 2 | 0.0019 | 0.0072 | 0.1057 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.4186 | 0.4729 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.095 | 0.1073 |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0138 | 0.3676 | 0.4154 |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0039 | 0.0677 | 1 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0044 | 0.0839 | 0.0839 |
Loa Loa (eye worm) | hypothetical protein | 0.0138 | 0.3676 | 0.4154 |
Onchocerca volvulus | 0.0017 | 0 | 0.5 | |
Onchocerca volvulus | 0.0017 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.