Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | enhancer of zeste ezh | 0.1073 | 1 | 1 |
Plasmodium vivax | ABC transporter G family member 2, putative | 0.0221 | 0.1786 | 0.5 |
Loa Loa (eye worm) | SET domain-containing protein | 0.1073 | 1 | 1 |
Mycobacterium tuberculosis | Probable conserved transmembrane ATP-binding protein ABC transporter | 0.0185 | 0.1437 | 0.5 |
Leishmania major | ATP-binding cassette protein subfamily G, member 6, putative | 0.0221 | 0.1786 | 1 |
Mycobacterium ulcerans | transmembrane ABC transporter ATP-binding protein | 0.0221 | 0.1786 | 0.5 |
Mycobacterium ulcerans | transmembrane ABC transporter ATP-binding protein | 0.0221 | 0.1786 | 0.5 |
Trypanosoma cruzi | ATP-binding cassette protein, putative | 0.0221 | 0.1786 | 1 |
Trypanosoma cruzi | ABC transporter, putative | 0.0221 | 0.1786 | 1 |
Giardia lamblia | ABC transporter | 0.0219 | 0.1761 | 0.5 |
Plasmodium falciparum | ABC transporter G family member 2 | 0.0221 | 0.1786 | 0.5 |
Toxoplasma gondii | ATP-binding cassette G family transporter ABCG84 | 0.0221 | 0.1786 | 1 |
Trypanosoma brucei | ABC transporter, putative | 0.0221 | 0.1786 | 1 |
Schistosoma mansoni | ATP-binding cassette sub-family g2 (white protein) (abcg2) | 0.0221 | 0.1786 | 0.0408 |
Trypanosoma brucei | ATP-binding cassette protein, putative | 0.0221 | 0.1786 | 1 |
Leishmania major | ATP-binding cassette protein subfamily G, member 4, putative | 0.0221 | 0.1786 | 1 |
Entamoeba histolytica | ABC transporter, putative | 0.0221 | 0.1786 | 0.5 |
Echinococcus granulosus | histone lysine N methyltransferase Ez | 0.1073 | 1 | 1 |
Schistosoma mansoni | ABC transporter | 0.0188 | 0.1461 | 0.0029 |
Mycobacterium ulcerans | transmembrane ABC transporter ATP-binding protein | 0.0221 | 0.1786 | 0.5 |
Echinococcus multilocularis | histone lysine N methyltransferase E(z) | 0.1073 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.