Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Inhibitor of Apoptosis domain containing protein | 0.0114 | 0.3715 | 1 |
Onchocerca volvulus | 0.0114 | 0.3715 | 0.5 | |
Onchocerca volvulus | Deterin homolog | 0.0114 | 0.3715 | 0.5 |
Brugia malayi | Inhibitor of Apoptosis domain containing protein | 0.0114 | 0.3715 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.3715 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 1 | 1 |
Echinococcus multilocularis | geminin | 0.0205 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.3715 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
AbsAC40_uM (binding) | 0.646 uM | PubChem BioAssay. MLPCN ERAP1 Measured in Biochemical System Using Plate Reader - 7016-01_Inhibitor_Dose_CherryPick_Activity. (absACnn = the concentration at which the curve crosses threshold nn uM) (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.