Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0571 | 0.5 | 0.5 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0571 | 0.5 | 0.5 |
Brugia malayi | Peptidase family M1 containing protein | 0.0571 | 0.5 | 0.5 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0571 | 0.5 | 0.5 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0571 | 0.5 | 0.5 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0571 | 0.5 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0571 | 0.5 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0571 | 0.5 | 0.5 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0571 | 0.5 | 0.5 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0571 | 0.5 | 0.5 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0571 | 0.5 | 0.5 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0571 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0571 | 0.5 | 0.5 | |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0571 | 0.5 | 0.5 |
Echinococcus granulosus | aminopeptidase N | 0.0571 | 0.5 | 0.5 |
Echinococcus multilocularis | aminopeptidase N | 0.0571 | 0.5 | 0.5 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0571 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0571 | 0.5 | 0.5 | |
Loa Loa (eye worm) | aminopeptidase N | 0.0571 | 0.5 | 0.5 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0571 | 0.5 | 0.5 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0571 | 0.5 | 0.5 |
Brugia malayi | hypothetical protein | 0.0571 | 0.5 | 0.5 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0571 | 0.5 | 0.5 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0571 | 0.5 | 0.5 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0571 | 0.5 | 0.5 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0571 | 0.5 | 0.5 |
Entamoeba histolytica | aminopeptidase, putative | 0.0571 | 0.5 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0571 | 0.5 | 0.5 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0571 | 0.5 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0571 | 0.5 | 0.5 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0571 | 0.5 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.