Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0088 | 0.4374 | 0.4374 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0088 | 0.4374 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0043 | 0.0796 | 0.1819 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0088 | 0.4374 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0088 | 0.4374 | 1 |
Echinococcus granulosus | small conductance calcium activated potassium | 0.0134 | 0.811 | 0.811 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0088 | 0.4374 | 0.4374 |
Schistosoma mansoni | alpha-glucosidase | 0.013 | 0.7808 | 0.7808 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0088 | 0.4374 | 1 |
Giardia lamblia | Kinase, PLK | 0.0088 | 0.4374 | 0.5 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0151 | 0.951 | 0.951 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0088 | 0.4374 | 1 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0088 | 0.4374 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0088 | 0.4374 | 1 |
Echinococcus multilocularis | small conductance calcium activated potassium | 0.0134 | 0.811 | 0.811 |
Schistosoma mansoni | hypothetical protein | 0.0157 | 1 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0151 | 0.951 | 1 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0151 | 0.951 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0151 | 0.951 | 0.951 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0127 | 0.7583 | 0.7583 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0034 | 0 | 0.5 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0088 | 0.4374 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0134 | 0.811 | 0.811 |
Schistosoma mansoni | alpha-glucosidase | 0.013 | 0.7808 | 0.7808 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0134 | 0.811 | 0.811 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0088 | 0.4374 | 0.4599 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 0.811 | 0.8528 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0088 | 0.4374 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.2157 | 0.2268 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2714 | 0.2853 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0151 | 0.951 | 0.951 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0088 | 0.4374 | 1 |
Trypanosoma brucei | polo-like protein kinase | 0.0088 | 0.4374 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0157 | 1 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0043 | 0.0796 | 0.1819 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0088 | 0.4374 | 0.4374 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0088 | 0.4374 | 1 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0088 | 0.4374 | 0.4599 |
Echinococcus multilocularis | geminin | 0.0157 | 1 | 1 |
Schistosoma mansoni | kinase | 0.0045 | 0.0889 | 0.0889 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0088 | 0.4374 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.