Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0151 | 0.951 | 0.951 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0127 | 0.7583 | 0.7583 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0151 | 0.951 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.2157 | 0.2268 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0088 | 0.4374 | 0.4599 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0151 | 0.951 | 0.951 |
Schistosoma mansoni | hypothetical protein | 0.0157 | 1 | 1 |
Echinococcus granulosus | small conductance calcium activated potassium | 0.0134 | 0.811 | 0.811 |
Trypanosoma brucei | polo-like protein kinase | 0.0088 | 0.4374 | 1 |
Echinococcus multilocularis | small conductance calcium activated potassium | 0.0134 | 0.811 | 0.811 |
Echinococcus multilocularis | geminin | 0.0157 | 1 | 1 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0088 | 0.4374 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0157 | 1 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0088 | 0.4374 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0088 | 0.4374 | 0.4374 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0134 | 0.811 | 0.811 |
Schistosoma mansoni | alpha-glucosidase | 0.013 | 0.7808 | 0.7808 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2714 | 0.2853 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0088 | 0.4374 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0088 | 0.4374 | 0.4374 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0151 | 0.951 | 0.951 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0088 | 0.4374 | 0.4599 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0034 | 0 | 0.5 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0088 | 0.4374 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0088 | 0.4374 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.013 | 0.7808 | 0.7808 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0088 | 0.4374 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 0.811 | 0.8528 |
Giardia lamblia | Kinase, PLK | 0.0088 | 0.4374 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0088 | 0.4374 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0134 | 0.811 | 0.811 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0088 | 0.4374 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0088 | 0.4374 | 1 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0088 | 0.4374 | 0.4374 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0088 | 0.4374 | 1 |
Schistosoma mansoni | kinase | 0.0045 | 0.0889 | 0.0889 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0088 | 0.4374 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0088 | 0.4374 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0043 | 0.0796 | 0.1819 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0043 | 0.0796 | 0.1819 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0151 | 0.951 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.