Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | allatostatin A receptor | 0.0043 | 0.6648 | 0.5651 |
Brugia malayi | FAD binding domain containing protein | 0.0051 | 1 | 1 |
Plasmodium falciparum | nitric oxide synthase, putative | 0.0051 | 1 | 0.5 |
Schistosoma mansoni | opsin-like receptor | 0.0043 | 0.6648 | 0.6648 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | serotonin receptor | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0043 | 0.6648 | 0.5651 |
Brugia malayi | neuropeptide F receptor | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | NADPH cytochrome P450 reductase | 0.0051 | 1 | 1 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0043 | 0.6648 | 0.6648 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | sex peptide receptor | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Trypanosoma brucei | NADPH-cytochrome p450 reductase, putative | 0.0051 | 1 | 0.5 |
Brugia malayi | sulfakinin receptor protein | 0.0043 | 0.6648 | 0.5651 |
Onchocerca volvulus | 0.0043 | 0.6648 | 0.5 | |
Brugia malayi | Melatonin receptor type 1A | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0043 | 0.6648 | 0.5651 |
Onchocerca volvulus | 0.0043 | 0.6648 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Onchocerca volvulus | 0.0043 | 0.6648 | 0.5 | |
Echinococcus multilocularis | neuropeptide receptor | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0043 | 0.6648 | 0.5651 |
Onchocerca volvulus | 0.0043 | 0.6648 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 1 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0043 | 0.6648 | 0.6648 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0043 | 0.6648 | 0.6648 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0043 | 0.6648 | 0.5651 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.0051 | 1 | 0.5 |
Echinococcus granulosus | somatostatin receptor | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | neuropeptide receptor | 0.0043 | 0.6648 | 0.6648 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Brugia malayi | neuropeptide F receptor | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0043 | 0.6648 | 0.5651 |
Brugia malayi | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0043 | 0.6648 | 0.5651 |
Onchocerca volvulus | 0.0043 | 0.6648 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | g protein coupled receptor | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.6648 | 0.6648 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | NADPH dependent diflavin oxidoreductase 1 | 0.0051 | 1 | 1 |
Schistosoma mansoni | amine GPCR | 0.0043 | 0.6648 | 0.6648 |
Brugia malayi | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Onchocerca volvulus | 0.0043 | 0.6648 | 0.5 | |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0043 | 0.6648 | 0.5651 |
Brugia malayi | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Brugia malayi | Serotonin receptor | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.6648 | 0.6648 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0043 | 0.6648 | 0.6648 |
Onchocerca volvulus | 0.0043 | 0.6648 | 0.5 | |
Trypanosoma cruzi | p450 reductase, putative | 0.0051 | 1 | 0.5 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0043 | 0.6648 | 0.5651 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | myosin xvIII | 0.0043 | 0.6648 | 0.6648 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0043 | 0.6648 | 0.6648 |
Schistosoma mansoni | biogenic amine receptor | 0.0043 | 0.6648 | 0.6648 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0043 | 0.6648 | 0.6648 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | amine GPCR | 0.0043 | 0.6648 | 0.6648 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0043 | 0.6648 | 0.6648 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | adenoreceptor | 0.0043 | 0.6648 | 0.6648 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0043 | 0.6648 | 0.5651 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0043 | 0.6648 | 0.5651 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0043 | 0.6648 | 0.5 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | g-protein coupled receptor | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0043 | 0.6648 | 0.6648 |
Echinococcus granulosus | neuropeptide s receptor | 0.0043 | 0.6648 | 0.5651 |
Brugia malayi | larval opioid receptor | 0.0043 | 0.6648 | 0.5651 |
Brugia malayi | Dopamine receptor | 0.0043 | 0.6648 | 0.5651 |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.0051 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Brugia malayi | G protein-coupled receptor | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0043 | 0.6648 | 0.5651 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.0051 | 1 | 0.5 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | g protein coupled receptor | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | neuropeptide receptor | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | orexin receptor type 2 | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0043 | 0.6648 | 0.5651 |
Mycobacterium ulcerans | formate dehydrogenase H FdhF | 0.0051 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0043 | 0.6648 | 0.5651 |
Trypanosoma cruzi | NADPH-dependent FMN/FAD containing oxidoreductase, putative | 0.0051 | 1 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0043 | 0.6648 | 0.6648 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.6648 | 0.6648 |
Brugia malayi | Dopamine receptor protein 2 | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | biogenic amine receptor | 0.0043 | 0.6648 | 0.6648 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0043 | 0.6648 | 0.6648 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0043 | 0.6648 | 0.6648 |
Brugia malayi | Dopamine receptor protein 1 | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.6648 | 0.6648 |
Schistosoma mansoni | histamine h1 receptor | 0.0043 | 0.6648 | 0.6648 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | opsin-like receptor | 0.0043 | 0.6648 | 0.6648 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0043 | 0.6648 | 0.6648 |
Onchocerca volvulus | 0.0043 | 0.6648 | 0.5 | |
Brugia malayi | GnHR receptor homolog | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0043 | 0.6648 | 0.5651 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0043 | 0.6648 | 0.6648 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | g protein coupled receptor | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | opsin-like receptor | 0.0043 | 0.6648 | 0.6648 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | g protein coupled receptor | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | g protein coupled receptor | 0.0043 | 0.6648 | 0.5651 |
Brugia malayi | follicle stimulating hormone receptor | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0043 | 0.6648 | 0.6648 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0043 | 0.6648 | 0.6648 |
Echinococcus granulosus | sex peptide receptor | 0.0043 | 0.6648 | 0.5651 |
Plasmodium vivax | NADPH-cytochrome p450 reductase, putative | 0.0051 | 1 | 1 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0043 | 0.6648 | 0.5651 |
Trichomonas vaginalis | sulfite reductase, putative | 0.0051 | 1 | 1 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0043 | 0.6648 | 0.6648 |
Echinococcus granulosus | NADPH dependent diflavin oxidoreductase 1 | 0.0051 | 1 | 1 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0043 | 0.6648 | 0.5651 |
Chlamydia trachomatis | sulfite reductase | 0.0032 | 0.2291 | 0.5 |
Echinococcus granulosus | g protein coupled receptor | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0043 | 0.6648 | 0.6648 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | biogenic amine receptor | 0.0043 | 0.6648 | 0.6648 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Brugia malayi | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0043 | 0.6648 | 0.5651 |
Brugia malayi | Serotonin receptor | 0.0043 | 0.6648 | 0.5651 |
Brugia malayi | G-protein coupled receptor | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0043 | 0.6648 | 0.6648 |
Echinococcus multilocularis | fmrfamide receptor | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0043 | 0.6648 | 0.5651 |
Onchocerca volvulus | 0.0043 | 0.6648 | 0.5 | |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.0051 | 1 | 0.5 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | neuropeptide receptor | 0.0043 | 0.6648 | 0.6648 |
Loa Loa (eye worm) | FAD binding domain-containing protein | 0.0051 | 1 | 1 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0043 | 0.6648 | 0.5651 |
Brugia malayi | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0043 | 0.6648 | 0.6648 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0043 | 0.6648 | 0.5651 |
Brugia malayi | ORL1-like opioid receptor | 0.0043 | 0.6648 | 0.5651 |
Brugia malayi | G-protein coupled receptor | 0.0043 | 0.6648 | 0.5651 |
Brugia malayi | RE15519p | 0.0043 | 0.6648 | 0.5651 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | neuropeptide receptor | 0.0043 | 0.6648 | 0.6648 |
Echinococcus granulosus | serotonin receptor | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0043 | 0.6648 | 0.6648 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | amine GPCR | 0.0043 | 0.6648 | 0.6648 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | allatostatin A receptor | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0043 | 0.6648 | 0.6648 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0043 | 0.6648 | 0.5651 |
Giardia lamblia | Nitric oxide synthase, inducible | 0.0045 | 0.7709 | 0.5 |
Onchocerca volvulus | 0.0043 | 0.6648 | 0.5 | |
Trypanosoma brucei | NADPH-dependent diflavin oxidoreductase 1 | 0.0051 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Brugia malayi | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Brugia malayi | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0043 | 0.6648 | 0.5651 |
Onchocerca volvulus | 0.0043 | 0.6648 | 0.5 | |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0043 | 0.6648 | 0.6648 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | neuropeptide receptor | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0043 | 0.6648 | 0.6648 |
Echinococcus multilocularis | somatostatin receptor | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | amine GPCR | 0.0043 | 0.6648 | 0.6648 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0043 | 0.6648 | 0.5651 |
Brugia malayi | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Leishmania major | NADPH-cytochrome p450 reductase-like protein | 0.0051 | 1 | 1 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0043 | 0.6648 | 0.6648 |
Onchocerca volvulus | 0.0043 | 0.6648 | 0.5 | |
Brugia malayi | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | serotonin receptor | 0.0043 | 0.6648 | 0.5651 |
Brugia malayi | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Onchocerca volvulus | 0.0043 | 0.6648 | 0.5 | |
Giardia lamblia | Hypothetical protein | 0.0045 | 0.7709 | 0.5 |
Leishmania major | p450 reductase, putative | 0.0051 | 1 | 1 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0043 | 0.6648 | 0.6648 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | neuropeptide receptor | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | NADPH cytochrome P450 reductase | 0.0051 | 1 | 1 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0043 | 0.6648 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0043 | 0.6648 | 0.6648 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | amine GPCR | 0.0043 | 0.6648 | 0.6648 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0043 | 0.6648 | 0.6648 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0043 | 0.6648 | 0.6648 |
Echinococcus multilocularis | fmrfamide receptor | 0.0043 | 0.6648 | 0.5651 |
Onchocerca volvulus | 0.0043 | 0.6648 | 0.5 | |
Onchocerca volvulus | 0.0043 | 0.6648 | 0.5 | |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | cytochrome P450 reductase | 0.0051 | 1 | 1 |
Onchocerca volvulus | 0.0043 | 0.6648 | 0.5 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0043 | 0.6648 | 0.6648 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase | 0.0032 | 0.2291 | 0.2291 |
Brugia malayi | AKH receptor | 0.0043 | 0.6648 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0043 | 0.6648 | 0.5651 |
Onchocerca volvulus | 0.0043 | 0.6648 | 0.5 | |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0043 | 0.6648 | 0.5651 |
Brugia malayi | putative neuropeptide receptor | 0.0043 | 0.6648 | 0.5651 |
Echinococcus granulosus | fmrfamide receptor | 0.0043 | 0.6648 | 0.5651 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0043 | 0.6648 | 0.5651 |
Schistosoma mansoni | neuropeptide receptor | 0.0043 | 0.6648 | 0.6648 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | = 56 % | Displacement of fluorescein-labeled ES2 from human recombinant ERbeta receptor at 100000 nM after 2 hrs by fluorescence polarization assay | ChEMBL. | 25751283 |
Activity (binding) | = 62 % | Displacement of fluorescein-labeled ES2 from human recombinant ERalpha receptor at 100000 nM after 2 hrs by fluorescence polarization assay | ChEMBL. | 25751283 |
IC50 (binding) | = 30500 nM | Inhibition of human recombinant aromatase using 7-methoxy-trifluoromethylcoumarin as substrate assessed as formation of fluorescent metabolite after 30 mins by fluorescence assay | ChEMBL. | 25751283 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.