Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Putative nachr subunit | 0.0131 | 0.2673 | 0.2673 |
Brugia malayi | Pre-SET motif family protein | 0.0252 | 0.6447 | 0.6447 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0131 | 0.2673 | 0.2817 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0131 | 0.2673 | 0.2817 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0131 | 0.2673 | 0.2817 |
Loa Loa (eye worm) | hypothetical protein | 0.0131 | 0.2673 | 0.2673 |
Onchocerca volvulus | 0.0131 | 0.2673 | 0.2673 | |
Echinococcus multilocularis | geminin | 0.0205 | 0.4987 | 0.5255 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.4987 | 0.5255 |
Loa Loa (eye worm) | hypothetical protein | 0.0131 | 0.2673 | 0.2673 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0131 | 0.2673 | 0.2817 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.3492 | 0.3492 |
Loa Loa (eye worm) | hypothetical protein | 0.0131 | 0.2673 | 0.2673 |
Onchocerca volvulus | 0.0287 | 0.7533 | 0.7533 | |
Loa Loa (eye worm) | hypothetical protein | 0.0175 | 0.4053 | 0.4053 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0131 | 0.2673 | 0.2817 |
Echinococcus granulosus | geminin | 0.0205 | 0.4987 | 0.5255 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.4987 | 0.5255 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0279 | 0.7274 | 0.5 |
Trichomonas vaginalis | set domain proteins, putative | 0.0287 | 0.7533 | 0.5 |
Echinococcus multilocularis | small conductance calcium activated potassium | 0.035 | 0.9489 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.035 | 0.9489 | 0.9489 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0333 | 0.8957 | 0.944 |
Schistosoma mansoni | calcium-activated potassium channel | 0.035 | 0.9489 | 1 |
Brugia malayi | Cation transporter family protein | 0.0131 | 0.2673 | 0.2673 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0131 | 0.2673 | 0.2673 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0131 | 0.2673 | 0.2673 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0131 | 0.2673 | 0.2817 |
Onchocerca volvulus | 0.0131 | 0.2673 | 0.2673 | |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0131 | 0.2673 | 0.2817 |
Echinococcus granulosus | small conductance calcium activated potassium | 0.035 | 0.9489 | 1 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0131 | 0.2673 | 0.2817 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0252 | 0.6447 | 0.6447 |
Onchocerca volvulus | 0.0131 | 0.2673 | 0.2673 | |
Schistosoma mansoni | hypothetical protein | 0.035 | 0.9489 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.2021 | 0.2021 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.