Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | Ceramide glucosyltransferase | 0.0131 | 0.4236 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 25.06 uM | Anticancer activity against human HT-29 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | ChEMBL. | 26330077 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.