Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | MDM2 proto-oncogene, E3 ubiquitin protein ligase | Starlite/ChEMBL | No references |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | SWI:SNF matrix associated | 0.0013 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0013 | 0.5 | 0.5 | |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0013 | 0.5 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.5 | 0.5 |
Chlamydia trachomatis | DNA topoisomerase I | 0.0013 | 0.5 | 0.5 |
Brugia malayi | SWIB/MDM2 domain containing protein | 0.0013 | 0.5 | 0.5 |
Plasmodium vivax | hypothetical protein, conserved | 0.0013 | 0.5 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.5 | 0.5 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0013 | 0.5 | 0.5 |
Loa Loa (eye worm) | SWIB/MDM2 domain-containing protein | 0.0013 | 0.5 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.5 | 0.5 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0013 | 0.5 | 0.5 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.0013 | 0.5 | 0.5 |
Loa Loa (eye worm) | brahma associated protein | 0.0013 | 0.5 | 0.5 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0013 | 0.5 | 0.5 |
Plasmodium vivax | SWIB/MDM2 domain-containing protein, putative | 0.0013 | 0.5 | 0.5 |
Echinococcus granulosus | Upstream activation factor subunit UAF30 | 0.0013 | 0.5 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.5 | 0.5 |
Brugia malayi | brahma associated protein 60 kDa | 0.0013 | 0.5 | 0.5 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0013 | 0.5 | 0.5 |
Chlamydia trachomatis | SWIB complex protein | 0.0013 | 0.5 | 0.5 |
Echinococcus multilocularis | Upstream activation factor subunit UAF30 | 0.0013 | 0.5 | 0.5 |
Schistosoma mansoni | brg-1 associated factor | 0.0013 | 0.5 | 0.5 |
Toxoplasma gondii | SWIB/MDM2 domain-containing protein | 0.0013 | 0.5 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.