Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | hypothetical protein | 0.0039 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0 | 0.5 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0125 | 0.8093 | 1 |
Brugia malayi | hypothetical protein | 0.0039 | 0 | 0.5 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0146 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | = 10 % | Inhibition of Glutathione S-transferase in P. yoelii nigeriensis isolated from infected mice (oral) | ChEMBL. | 10978190 |
Inhibition (binding) | = 10 % | Inhibition of Glutathione S-transferase in P. yoelii nigeriensis isolated from infected mice (oral) | ChEMBL. | 10978190 |
Inhibition (functional) | = 100 % | In Vitro inhibition of Heme Oxygenase in Cell-free parasite Plasmodium yoelii at concentration 10 microM | ChEMBL. | 10978190 |
Inhibition (functional) | = 100 % | In Vitro inhibition of Heme Oxygenase in Cell-free parasite Plasmodium yoelii at concentration 50 microM | ChEMBL. | 10978190 |
Inhibition (functional) | = 100 % | In Vitro inhibition of Heme Oxygenase in Cell-free parasite Plasmodium yoelii at concentration 100 microM | ChEMBL. | 10978190 |
Inhibition (functional) | = 100 % | In Vitro inhibition of Heme Oxygenase in Cell-free parasite Plasmodium yoelii at concentration 100 microM | ChEMBL. | 10978190 |
Inhibition (functional) | = 100 % | In Vitro inhibition of Heme Oxygenase in Cell-free parasite Plasmodium yoelii at concentration 10 microM | ChEMBL. | 10978190 |
Inhibition (functional) | = 100 % | In Vitro inhibition of Heme Oxygenase in Cell-free parasite Plasmodium yoelii at concentration 50 microM | ChEMBL. | 10978190 |
NI (functional) | Inhibition of heme oxygenase in P. yoelii nigeriensis isolated from infected mice (oral); NI denotes nil inhiibition | ChEMBL. | 10978190 | |
NI (functional) | In Vitro inhibition of Heme Oxygenase in Cell-free parasite Plasmodium yoelii at concentration 10 microM;NI denotes nil inhiibition | ChEMBL. | 10978190 | |
NI (functional) | In Vitro inhibition of Heme Oxygenase in Cell-free parasite Plasmodium yoelii at concentration 100 microM;NI denotes nil inhiibition | ChEMBL. | 10978190 | |
NI (functional) | In Vitro inhibition of Heme Oxygenase in Cell-free parasite Plasmodium yoelii at concentration 50 uM; NI denotes nil inhiibition | ChEMBL. | 10978190 | |
NI (functional) | 0 | In Vitro inhibition of Heme Oxygenase in Cell-free parasite Plasmodium yoelii at concentration 10 microM;NI denotes nil inhiibition | ChEMBL. | 10978190 |
NI (functional) | 0 | In Vitro inhibition of Heme Oxygenase in Cell-free parasite Plasmodium yoelii at concentration 50 uM; NI denotes nil inhiibition | ChEMBL. | 10978190 |
NI (functional) | 0 | In Vitro inhibition of Heme Oxygenase in Cell-free parasite Plasmodium yoelii at concentration 100 microM;NI denotes nil inhiibition | ChEMBL. | 10978190 |
NI (functional) | 0 | Inhibition of heme oxygenase in P. yoelii nigeriensis isolated from infected mice (oral); NI denotes nil inhiibition | ChEMBL. | 10978190 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.