Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | phosphorylase, glycogen | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0292 | 1 | 1 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0292 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0292 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0292 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0292 | 1 | 1 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0261 | 0.8242 | 0.5 |
Echinococcus granulosus | glycogen phosphorylase | 0.0261 | 0.8242 | 0.5 |
Loa Loa (eye worm) | glutaminase | 0.0273 | 0.8947 | 1 |
Echinococcus granulosus | glycogen phosphorylase | 0.0261 | 0.8242 | 0.5 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.0261 | 0.8242 | 0.5 |
Trichomonas vaginalis | glutaminase, putative | 0.0273 | 0.8947 | 0.4011 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0143 | 0.1674 | 0.5 |
Chlamydia trachomatis | glycogen phosphorylase | 0.0261 | 0.8242 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0292 | 1 | 1 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0261 | 0.8242 | 0.8242 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0292 | 1 | 1 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0143 | 0.1674 | 1 |
Loa Loa (eye worm) | glutaminase 2 | 0.0273 | 0.8947 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0292 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0292 | 1 | 1 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0143 | 0.1674 | 0.1871 |
Schistosoma mansoni | glycogen phosphorylase | 0.0261 | 0.8242 | 0.9212 |
Mycobacterium ulcerans | glutaminase | 0.0273 | 0.8947 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0292 | 1 | 1 |
Schistosoma mansoni | glycogen phosphorylase | 0.0261 | 0.8242 | 0.9212 |
Schistosoma mansoni | glutaminase | 0.0273 | 0.8947 | 1 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0261 | 0.8242 | 0.5 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0292 | 1 | 0.5 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.0261 | 0.8242 | 0.5 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.0261 | 0.8242 | 0.5 |
Brugia malayi | glutaminase DH11.1 | 0.0273 | 0.8947 | 1 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0261 | 0.8242 | 0.8242 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 11 nM | Inhibitory activity of the compound against rabbit muscle glycogen phosphorylase a | ChEMBL. | 15214781 |
Ki (binding) | = 11 nM | Inhibitory activity of the compound against rabbit muscle glycogen phosphorylase a | ChEMBL. | 15214781 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.