Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | CAAX amino terminal protease family protein | 0.0006 | 0 | 0.5 |
Toxoplasma gondii | hypothetical protein | 0.0006 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable integral membrane protein | 0.0006 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 1 | 0.5 |
Schistosoma mansoni | family U48 unassigned peptidase (U48 family) | 0.0029 | 1 | 1 |
Entamoeba histolytica | CAAX prenyl protease family | 0.0029 | 1 | 1 |
Plasmodium vivax | protease, putative | 0.0006 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable conserved integral membrane protein | 0.0006 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable conserved integral membrane protein | 0.0006 | 0 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0006 | 0 | 0.5 |
Echinococcus multilocularis | CAAX prenyl protease 2 | 0.0029 | 1 | 0.5 |
Leishmania major | CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) | 0.0029 | 1 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0006 | 0 | 0.5 |
Trypanosoma cruzi | peptidase with unknown catalytic mechanism (family U48) | 0.0029 | 1 | 0.5 |
Plasmodium falciparum | protease, putative | 0.0006 | 0 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0006 | 0 | 0.5 |
Treponema pallidum | hypothetical protein | 0.0006 | 0 | 0.5 |
Mycobacterium ulcerans | integral membrane protein | 0.0006 | 0 | 0.5 |
Echinococcus granulosus | CAAX prenyl protease 2 | 0.0029 | 1 | 0.5 |
Giardia lamblia | Hypothetical protein | 0.0029 | 1 | 0.5 |
Chlamydia trachomatis | hypothetical protein | 0.0006 | 0 | 0.5 |
Trypanosoma cruzi | CAAX prenyl protease 2, putative | 0.0029 | 1 | 0.5 |
Trichomonas vaginalis | Clan U, family U48, CaaX prenyl peptidase 2-like | 0.0029 | 1 | 0.5 |
Toxoplasma gondii | hypothetical protein | 0.0006 | 0 | 0.5 |
Schistosoma mansoni | family U48 unassigned peptidase (U48 family) | 0.0029 | 1 | 1 |
Trypanosoma brucei | CAAX amino terminal protease, putative | 0.0029 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.