Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0036 | 0.0053 | 0.0055 |
Schistosoma mansoni | sodium-bile acid cotransporter related | 0.0106 | 0.9595 | 1 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0036 | 0.0053 | 0.5 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0036 | 0.0053 | 0.5 |
Leishmania major | cell division related protein kinase 2,cdc2-related kinase | 0.0036 | 0.0053 | 0.5 |
Plasmodium falciparum | protein kinase 5 | 0.0036 | 0.0053 | 0.5 |
Giardia lamblia | Kinase, CMGC CDK | 0.0036 | 0.0053 | 0.5 |
Schistosoma mansoni | sodium-bile acid cotransporter | 0.0063 | 0.3714 | 0.3837 |
Plasmodium vivax | protein kinase Crk2 | 0.0036 | 0.0053 | 0.5 |
Toxoplasma gondii | cell-cycle-associated protein kinase CDK, putative | 0.0036 | 0.0053 | 0.5 |
Loa Loa (eye worm) | CMGC/CDK/CDK5 protein kinase | 0.0036 | 0.0053 | 0.0055 |
Giardia lamblia | Kinase, CMGC CDK | 0.0036 | 0.0053 | 0.5 |
Echinococcus multilocularis | sodium bile acid cotransporter | 0.0106 | 0.9595 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0036 | 0.0053 | 0.5 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0036 | 0.0053 | 0.0055 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0036 | 0.0053 | 0.5 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0036 | 0.0053 | 0.5 |
Echinococcus multilocularis | sodium bile acid cotransporter | 0.0106 | 0.9595 | 1 |
Schistosoma mansoni | sodium-bile acid cotransporter related | 0.0043 | 0.0972 | 0.0964 |
Onchocerca volvulus | 0.0106 | 0.9595 | 0.5 | |
Echinococcus multilocularis | sodium bile acid cotransporter | 0.0106 | 0.9595 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.9595 | 1 |
Echinococcus granulosus | sodium bile acid cotransporter | 0.0106 | 0.9595 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0036 | 0.0053 | 0.5 |
Echinococcus granulosus | sodium bile acid cotransporter | 0.0106 | 0.9595 | 1 |
Trypanosoma brucei | cdc2-related kinase 1 | 0.0036 | 0.0053 | 0.5 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0036 | 0.0053 | 0.5 |
Trypanosoma brucei | cdc2-related kinase 3 | 0.0036 | 0.0053 | 0.5 |
Mycobacterium ulcerans | epoxide hydrolase EphA | 0.0109 | 1 | 0.5 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0036 | 0.0053 | 0.5 |
Brugia malayi | Sodium Bile acid symporter family protein | 0.0106 | 0.9595 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0036 | 0.0053 | 0.5 |
Leishmania major | cell division protein kinase 2,cdc2-related kinase | 0.0036 | 0.0053 | 0.5 |
Echinococcus granulosus | sodium bile acid cotransporter | 0.0106 | 0.9595 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.