Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.1071 | 0.1071 |
Brugia malayi | hypothetical protein | 0.0125 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.1071 | 0.1071 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0238 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 1 | 1 |
Echinococcus multilocularis | glutamine synthetase | 0.0127 | 0.1222 | 0.1222 |
Onchocerca volvulus | 0.0238 | 1 | 1 | |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0238 | 1 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0238 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0238 | 1 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0238 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0238 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0238 | 1 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0238 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0238 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 1 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0238 | 1 | 1 |
Brugia malayi | steroid hormone receptor | 0.0238 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0238 | 1 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0238 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0125 | 0.1071 | 0.1071 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0238 | 1 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0125 | 0.1071 | 0.1071 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0238 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0238 | 1 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0238 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0125 | 0.1071 | 0.1071 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0238 | 1 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0238 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0238 | 1 | 1 |
Echinococcus granulosus | glutamine synthetase | 0.0127 | 0.1222 | 0.1222 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0238 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0238 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0238 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.1071 | 0.1071 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0238 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0238 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0238 | 1 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0238 | 1 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0125 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0238 | 1 | 1 |
Trypanosoma brucei | glutamine synthetase, putative | 0.0127 | 0.1222 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0238 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0238 | 1 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0238 | 1 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0238 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0238 | 1 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0238 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0238 | 1 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0238 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 1 | 1 |
Leishmania major | glutamine synthetase, putative | 0.0127 | 0.1222 | 0.5 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0238 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0125 | 0.1071 | 0.1071 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0238 | 1 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0238 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0238 | 1 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0238 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0238 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0238 | 1 | 1 |
Schistosoma mansoni | glutamine synthetase 1 2 (glutamate-amonia ligase) (gs) | 0.0127 | 0.1222 | 0.1222 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0238 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0238 | 1 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0125 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0125 | 0.1071 | 0.1071 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0238 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0238 | 1 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0238 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0125 | 0.1071 | 0.1071 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0238 | 1 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0125 | 0.1071 | 0.1071 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0238 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0238 | 1 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0238 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 1 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0238 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0238 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 1 | 1 |
Trypanosoma cruzi | glutamine synthetase, putative | 0.0127 | 0.1222 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0238 | 1 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0238 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0238 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0238 | 1 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0238 | 1 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0238 | 1 | 1 |
Trypanosoma cruzi | glutamine synthetase, putative | 0.0127 | 0.1222 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0238 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.