Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | oligomeric golgi complex subunit 3 | 0.0005 | 0.0363 | 0.0363 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0005 | 0.0363 | 0.0363 |
Echinococcus multilocularis | cyclin A3 4 | 0.0005 | 0.0363 | 0.0363 |
Echinococcus multilocularis | cyclin k | 0.0005 | 0.0363 | 0.0363 |
Trichomonas vaginalis | cyclin B, putative | 0.0021 | 0.2926 | 0.2659 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0021 | 0.2926 | 0.2926 |
Entamoeba histolytica | ras-1, putative | 0.0065 | 1 | 1 |
Trichomonas vaginalis | cyclins, putative | 0.0021 | 0.2926 | 0.2659 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0021 | 0.2926 | 0.2926 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0005 | 0.0363 | 0.0363 |
Trypanosoma brucei | mitotic cyclin 6 | 0.0021 | 0.2926 | 1 |
Echinococcus multilocularis | cyclin t1 | 0.0005 | 0.0363 | 0.0363 |
Echinococcus multilocularis | cyclin y | 0.0005 | 0.0363 | 0.0363 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0005 | 0.0363 | 0.0363 |
Echinococcus multilocularis | cyclins | 0.0021 | 0.2926 | 0.2926 |
Giardia lamblia | Cyclin A | 0.0021 | 0.2926 | 1 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0021 | 0.2926 | 0.2926 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0005 | 0.0363 | 0.0363 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0005 | 0.0363 | 0.0363 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0005 | 0.0363 | 0.0363 |
Trichomonas vaginalis | dexras1, putative | 0.0065 | 1 | 1 |
Loa Loa (eye worm) | CYL-1 protein | 0.0005 | 0.0363 | 0.0363 |
Trichomonas vaginalis | cyclins, putative | 0.0021 | 0.2926 | 0.2659 |
Entamoeba histolytica | cyclin family protein | 0.0021 | 0.2926 | 0.2659 |
Trichomonas vaginalis | GTP-binding protein rit, putative | 0.0065 | 1 | 1 |
Echinococcus multilocularis | G2:mitotic specific cyclin B3 | 0.0021 | 0.2926 | 0.2926 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 1 | 1 |
Trichomonas vaginalis | cyclins, putative | 0.0021 | 0.2926 | 0.2659 |
Echinococcus multilocularis | cyclin B | 0.0021 | 0.2926 | 0.2926 |
Plasmodium falciparum | cyclin | 0.0021 | 0.2926 | 1 |
Entamoeba histolytica | cyclin family protein | 0.0021 | 0.2926 | 0.2659 |
Plasmodium vivax | cyclin homologue, putative | 0.0005 | 0.0363 | 0.5 |
Brugia malayi | Cyclin C | 0.0005 | 0.0363 | 0.0363 |
Giardia lamblia | Hypothetical protein | 0.0021 | 0.2926 | 1 |
Plasmodium vivax | cyclin dependent kinase binding protein, putative | 0.0005 | 0.0363 | 0.5 |
Echinococcus granulosus | cyclin y | 0.0005 | 0.0363 | 0.0363 |
Trichomonas vaginalis | cyclin D, putative | 0.0021 | 0.2926 | 0.2659 |
Plasmodium vivax | hypothetical protein, conserved | 0.0005 | 0.0363 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0363 | 0.0363 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0005 | 0.0363 | 0.0363 |
Schistosoma mansoni | proteasome subunit alpha 1 (T01 family) | 0.0005 | 0.0363 | 0.124 |
Schistosoma mansoni | cyclin k | 0.0005 | 0.0363 | 0.124 |
Schistosoma mansoni | g1/s-specific cyclin C | 0.0005 | 0.0363 | 0.124 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0021 | 0.2926 | 0.2926 |
Echinococcus multilocularis | cyclin y | 0.0005 | 0.0363 | 0.0363 |
Toxoplasma gondii | hypothetical protein | 0.0016 | 0.211 | 1 |
Onchocerca volvulus | Protein CNPPD1 homolog | 0.0005 | 0.0363 | 0.124 |
Schistosoma mansoni | cyclin B3 | 0.0021 | 0.2926 | 1 |
Echinococcus granulosus | cyclin G2 | 0.0005 | 0.0363 | 0.0363 |
Trichomonas vaginalis | ras-dva small GTPase, putative | 0.0065 | 1 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.0021 | 0.2926 | 0.2659 |
Trypanosoma cruzi | CYC2-like cyclin, putative | 0.0021 | 0.2926 | 1 |
Echinococcus granulosus | cyclins | 0.0021 | 0.2926 | 0.2926 |
Echinococcus granulosus | cyclin G2 | 0.0005 | 0.0363 | 0.0363 |
Echinococcus multilocularis | Cyclin L1 | 0.0005 | 0.0363 | 0.0363 |
Loa Loa (eye worm) | Ras protein let-60 | 0.0065 | 1 | 1 |
Schistosoma mansoni | cyclin B | 0.0021 | 0.2926 | 1 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0005 | 0.0363 | 0.0363 |
Trypanosoma cruzi | cyclin 6, putative | 0.0021 | 0.2926 | 1 |
Plasmodium vivax | cyclin 4, putative | 0.0005 | 0.0363 | 0.5 |
Trichomonas vaginalis | cyclin A, putative | 0.0021 | 0.2926 | 0.2659 |
Trypanosoma cruzi | cyclin, putative | 0.0021 | 0.2926 | 1 |
Schistosoma mansoni | cyclin d | 0.0005 | 0.0363 | 0.124 |
Echinococcus multilocularis | cyclin | 0.0005 | 0.0363 | 0.0363 |
Echinococcus multilocularis | oligomeric golgi complex subunit 3 | 0.0005 | 0.0363 | 0.0363 |
Trichomonas vaginalis | cyclin B, putative | 0.0021 | 0.2926 | 0.2659 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0005 | 0.0363 | 0.0363 |
Brugia malayi | Ras-related protein R-Ras2 | 0.0065 | 1 | 1 |
Trichomonas vaginalis | ral, putative | 0.0065 | 1 | 1 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0005 | 0.0363 | 0.0363 |
Echinococcus multilocularis | cyclin B3 1 | 0.0021 | 0.2926 | 0.2926 |
Schistosoma mansoni | cyclin G | 0.0005 | 0.0363 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.2926 | 0.2926 |
Onchocerca volvulus | Cyclin L homolog | 0.0005 | 0.0363 | 0.124 |
Trichomonas vaginalis | cyclin B3, putative | 0.0021 | 0.2926 | 0.2659 |
Echinococcus multilocularis | cyclin G2 | 0.0005 | 0.0363 | 0.0363 |
Echinococcus multilocularis | cyclins | 0.0021 | 0.2926 | 0.2926 |
Entamoeba histolytica | cyclin, putative | 0.0021 | 0.2926 | 0.2659 |
Entamoeba histolytica | Ras family GTPase | 0.0065 | 1 | 1 |
Onchocerca volvulus | 0.0021 | 0.2926 | 1 | |
Echinococcus multilocularis | cyclin G2 | 0.0005 | 0.0363 | 0.0363 |
Onchocerca volvulus | 0.0005 | 0.0363 | 0.124 | |
Echinococcus multilocularis | cyclins | 0.0021 | 0.2926 | 0.2926 |
Echinococcus granulosus | cyclin y | 0.0005 | 0.0363 | 0.0363 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0021 | 0.2926 | 0.2659 |
Loa Loa (eye worm) | cyclin C | 0.0005 | 0.0363 | 0.0363 |
Echinococcus granulosus | cyclin k | 0.0005 | 0.0363 | 0.0363 |
Trichomonas vaginalis | cyclins, putative | 0.0021 | 0.2926 | 0.2659 |
Echinococcus granulosus | cyclins | 0.0021 | 0.2926 | 0.2926 |
Schistosoma mansoni | Cyclin fold protein | 0.0005 | 0.0363 | 0.124 |
Loa Loa (eye worm) | cyclin fold protein 1 variant b | 0.0005 | 0.0363 | 0.0363 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0363 | 0.0363 |
Echinococcus granulosus | G2:mitotic specific cyclin B3 | 0.0021 | 0.2926 | 0.2926 |
Echinococcus multilocularis | cyclins | 0.0021 | 0.2926 | 0.2926 |
Echinococcus granulosus | cyclin B3 1 | 0.0021 | 0.2926 | 0.2926 |
Trichomonas vaginalis | cyclin B, putative | 0.0021 | 0.2926 | 0.2659 |
Schistosoma mansoni | cyclins | 0.0021 | 0.2926 | 1 |
Trypanosoma cruzi | cyclin, putative | 0.0021 | 0.2926 | 1 |
Echinococcus granulosus | cyclin B | 0.0021 | 0.2926 | 0.2926 |
Echinococcus multilocularis | G1:S specific cyclin D1 | 0.0005 | 0.0363 | 0.0363 |
Leishmania major | CYC2-like cyclin, putative,cyclin 6, putative | 0.0021 | 0.2926 | 1 |
Echinococcus granulosus | cyclin A3 4 | 0.0005 | 0.0363 | 0.0363 |
Echinococcus multilocularis | cyclin b3 | 0.0021 | 0.2926 | 0.2926 |
Entamoeba histolytica | cyclin, putative | 0.0021 | 0.2926 | 0.2659 |
Echinococcus multilocularis | cyclins | 0.0021 | 0.2926 | 0.2926 |
Echinococcus granulosus | Cyclin L1 | 0.0005 | 0.0363 | 0.0363 |
Brugia malayi | cyclin fold protein 1 variant b | 0.0005 | 0.0363 | 0.0363 |
Echinococcus multilocularis | cyclins | 0.0021 | 0.2926 | 0.2926 |
Echinococcus granulosus | cyclins | 0.0021 | 0.2926 | 0.2926 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0363 | 0.0363 |
Schistosoma mansoni | hypothetical protein | 0.0005 | 0.0363 | 0.124 |
Leishmania major | cyclin | 0.0021 | 0.2926 | 1 |
Echinococcus granulosus | cyclins | 0.0021 | 0.2926 | 0.2926 |
Schistosoma mansoni | hypothetical protein | 0.0005 | 0.0363 | 0.124 |
Loa Loa (eye worm) | cyclin domain-containing protein | 0.0005 | 0.0363 | 0.0363 |
Echinococcus multilocularis | cdk5 and abl1 enzyme substrate 1 | 0.0005 | 0.0363 | 0.0363 |
Entamoeba histolytica | Ras family GTPase | 0.0065 | 1 | 1 |
Trichomonas vaginalis | cyclins, putative | 0.0021 | 0.2926 | 0.2659 |
Trichomonas vaginalis | cyclin D, putative | 0.0021 | 0.2926 | 0.2659 |
Echinococcus granulosus | cyclin t1 | 0.0005 | 0.0363 | 0.0363 |
Giardia lamblia | G2/mitotic-specific cyclin B | 0.0021 | 0.2926 | 1 |
Echinococcus multilocularis | ras gtpase | 0.0065 | 1 | 1 |
Echinococcus granulosus | cyclin b3 | 0.0021 | 0.2926 | 0.2926 |
Echinococcus granulosus | cyclins | 0.0005 | 0.0363 | 0.0363 |
Echinococcus granulosus | cdk5 and abl1 enzyme substrate 1 | 0.0005 | 0.0363 | 0.0363 |
Echinococcus granulosus | ras gtpase | 0.0065 | 1 | 1 |
Echinococcus granulosus | cyclin | 0.0005 | 0.0363 | 0.0363 |
Onchocerca volvulus | Cyclin L homolog | 0.0005 | 0.0363 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0363 | 0.0363 |
Trichomonas vaginalis | rheb, putative | 0.0065 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.2926 | 0.2926 |
Trichomonas vaginalis | rap1 and, putative | 0.0065 | 1 | 1 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0005 | 0.0363 | 0.0363 |
Trichomonas vaginalis | cyclin B, putative | 0.0021 | 0.2926 | 0.2659 |
Schistosoma mansoni | cyclin l | 0.0005 | 0.0363 | 0.124 |
Echinococcus granulosus | cyclins | 0.0021 | 0.2926 | 0.2926 |
Schistosoma mansoni | cyclin G2 | 0.0005 | 0.0363 | 0.124 |
Echinococcus granulosus | G1:S specific cyclin D1 | 0.0005 | 0.0363 | 0.0363 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.0005 | 0.0363 | 0.0363 |
Echinococcus multilocularis | cyclins | 0.0021 | 0.2926 | 0.2926 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.