Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0123 | 0 | 0.5 |
Entamoeba histolytica | hydrolase, alpha/beta fold family domain containing protein | 0.0168 | 1 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0168 | 1 | 0.5 |
Trichomonas vaginalis | valacyclovir hydrolase, putative | 0.0168 | 1 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0168 | 1 | 0.5 |
Leishmania major | monoglyceride lipase, putative | 0.0168 | 1 | 0.5 |
Brugia malayi | amidase | 0.0123 | 0 | 0.5 |
Trypanosoma brucei | monoglyceride lipase, putative | 0.0168 | 1 | 0.5 |
Plasmodium falciparum | lysophospholipase, putative | 0.0168 | 1 | 0.5 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.0123 | 0 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0168 | 1 | 0.5 |
Mycobacterium leprae | POSSIBLE LYSOPHOSPHOLIPASE | 0.0168 | 1 | 0.5 |
Plasmodium falciparum | lysophospholipase, putative | 0.0168 | 1 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0168 | 1 | 0.5 |
Trypanosoma brucei | monoglyceride lipase, putative | 0.0168 | 1 | 0.5 |
Mycobacterium ulcerans | lysophospholipase | 0.0168 | 1 | 0.5 |
Plasmodium falciparum | lysophospholipase, putative | 0.0168 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0 | 0.5 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0123 | 0 | 0.5 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0123 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0168 | 1 | 0.5 |
Mycobacterium tuberculosis | Possible lysophospholipase | 0.0168 | 1 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0168 | 1 | 0.5 |
Schistosoma mansoni | amidase | 0.0123 | 0 | 0.5 |
Trypanosoma cruzi | monoglyceride lipase, putative | 0.0168 | 1 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0168 | 1 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0168 | 1 | 0.5 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0123 | 0 | 0.5 |
Plasmodium falciparum | esterase, putative | 0.0168 | 1 | 0.5 |
Plasmodium vivax | PST-A protein | 0.0168 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.