Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | inorganic polyphosphate/ATP-NAD kinase | 0.0691 | 1 | 0.5 |
Trichomonas vaginalis | poly(p)/ATP NAD kinase, putative | 0.0691 | 1 | 0.5 |
Trichomonas vaginalis | poly(p)/ATP NAD kinase, putative | 0.0691 | 1 | 0.5 |
Giardia lamblia | Inorganic polyphosphate/ATP-NAD kinase, putative | 0.0691 | 1 | 0.5 |
Treponema pallidum | hypothetical protein | 0.0691 | 1 | 0.5 |
Schistosoma mansoni | poly(p)/ATP NAD kinase | 0.0691 | 1 | 0.5 |
Mycobacterium leprae | Inorganic polyphosphate/ATP-NAD kinase PpnK (Poly(P)/ATP NAD kinase) | 0.0635 | 0 | 0.5 |
Echinococcus multilocularis | NAD kinase | 0.0691 | 1 | 0.5 |
Mycobacterium tuberculosis | Inorganic polyphosphate/ATP-NAD kinase PpnK (poly(P)/ATP NAD kinase) | 0.0635 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.